Thermo Fisher Scientific’s New ETD Mass Spectrometry Technology Wins Silver Award at PITTCON 2007

13 Mar 2007

Product news

Thermo Fisher Scientific Inc., the world leader in serving science, received the Silver Editors’ Award at PITTCON® 2007, the largest North American conference and exposition on laboratory science and instrumentation.

PITTCON editors voted the new Thermo Scientific LTQ XL™ linear ion trap mass spectrometer featuring Electron Transfer Dissociation (ETD) technology, one of the best new product innovations of the event, which featured more than 1000 exhibitors.

Available for the first time on a linear ion trap mass spectrometer, ETD provides important new peptide structural information not available from conventional collisionally induced dissociation (CID) methods. ETD is a new fragmentation technique that significantly improves protein characterization, post-translational modification (PTM) analysis and top-down or middle-down sequencing of proteins and peptides. The new Thermo Scientific LTQ XL is the only mass spectrometer that offers multiple dissociation techniques, Pulsed Q Dissociation (PQD), ETD and CID.

“We believe ETD performed on a linear ion trap is a major turning point for the proteomics community, enabling researchers to pinpoint, identify and fully characterize more post-transitional modificatons such as phosphorylation and glycosylation than ever before,” said Greg Herrema, president of Scientific Instruments at Thermo Fisher Scientific. Recognition for ETD at PITTCON 2007 follows last year’s PITTCON Gold Editors’ Award for the Thermo Scientific LTQ Orbitrap™ hybrid mass spectrometer.

Taking advantage of the high ion storage capacity and fast cycle times of linear ion trap technology, the LTQ XL with ETD is the only integrated mass spectrometry solution allowing researchers to conduct rapid, alternating CID and ETD experiments during LC/MSn analysis of complex samples. ETD data is easily processed using a new version of BioWorks™ software – both CID and ETD spectra are searched independently, with results from both searches combined for easy sorting and comparison. This new system provides the most complete view of a proteome currently available.

Thermo Fisher Scientific showcased a wide range of innovative new products and laboratory solutions at PITTCON 2007, offering customers integrated technology and services, from sample preparation and analysis to data interpretation and storage.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.
Thermo Fisher Scientific’s New ETD Mass Spectrometry Technology Wins Silver Award at PITTCON 2007