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Thermo Fisher Scientific Offers New ChIP Kt for the Study of Gene Regulation and Epigenetics

18 Mar 2010
Sarah Sarah
Marketing / Sales

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Thermo Fisher Scientific introduces the Thermo Scientific Pierce Agarose ChIP Kit for fast and reproducible chromatin immunoprecipitation (ChIP) assays. ChIP assays monitor transcription regulation through histone modification or transcription factor-DNA binding interactions. The ChIP technique captures a snapshot of specific protein-DNA interactions as they occur in living cells.

The Pierce® Agarose ChIP Assay Kit contains all reagents to perform a successful ChIP assay using mammalian cells or tissue. The specially titrated and tested micrococcal nuclease evenly digests the DNA, eliminating the variability that results from using sonication. The specially blocked ChIP Grade Pierce Protein A/G Plus Agarose Resin provides high binding capacity and low background. The fast procedure uses convenient spin columns for the immunoprecipitation, wash and elution steps, minimizing sample loss. The kit is compatible with any ChIP-grade antibody

Each Pierce Agarose ChIP Assay Kit contains sufficient reagents for 30 reactions. The Chromatin Prep Module, ChIP Protein A/G Plus Agarose and Proteinase K are also available separately.

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Cell Adhesion AssaysCell adhesion assays are used to quantitate attachment and analyze the molecular mechanisms for extracellular matrix adhesion, cell migration and sensitivity to inhibitors. Find the best cell adhesion assay equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Thermo Fisher Scientific Offers New ChIP Kt for the Study of Gene Regulation and Epigenetics