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Thermo Fisher Scientific Launches Technical Library on LC-MS Solutions for Endocrine Drug Analysis in Clinical Research

Thermo Fisher Scientific
11 Nov 2011
Roger Wayman
Administrator / Office Personnel

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Thermo Fisher Scientific Inc. has launched a new technical library of liquid chromatography-mass spectrometry (LC-MS) solutions for endocrine drug analysis in clinical research, including methods showcasing the ability of automated sample preparation and multiplexing to reduce sample preparation time and maximize mass spectrometer throughput.

The regularly updated technical library comprises detailed publications from Thermo Fisher’s dedicated global clinical research team, which develops faster and more analytically sensitive methods for endocrine drug analysis for its research clients. The new library is a comprehensive resource containing application notes, webinars, technical posters, case studies, videos and web resources for numerous applications.

“We designed the LC-MS technical library for endocrine drug analysis to help laboratory managers and technicians better understand the power of LC-MS technology for clinical research. We believe what they learn from this great resource will help maximize their sample throughput, improve turnaround time and reduce overall analysis cost, without compromising data quality for drug analysis,” said Ian Jardine, vice president of global R&D, Thermo Fisher.

The technical library includes the latest applications utilized for the analysis of endocrine drugs in clinical research, including:

- Immunoaffinity for research analysis of 1,25D
- Automated online sample preparation for time savings
- UHPLC for higher throughput
- Triple stage quadrupole for necessary LOQ and dynamic range
- High-resolution, accurate mass for difficult endogenous molecules.

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Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.

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Thermo Fisher Scientific Launches Technical Library on LC-MS Solutions for Endocrine Drug Analysis in Clinical Research