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Thermo Fisher Scientific Introduces Flexible, Adaptable Column for Nanoscale HPLC

15 Mar 2011
bridget bridget
Laboratory Director

Product news

Thermo Fisher Scientific Inc., the world leader in serving science, today announced the release of the Thermo Scientific EASY-Column for nanoscale HPLC applications. Nanoscale HPLC is primarily used in combination with high performance mass spectrometry for the analysis of complex biological samples, such as applications in proteomics and disease biomarker discovery.

The EASY-Column™ operates effectively on any nano LC system, including the Thermo Scientific EASY-nLC, and it is optimized for online LC-MS. Produced with the highest-quality and purest chromatography media possible, the EASY-Column uses metal-free fused silica capillaries to ensure full biocompatibility and has been designed to optimize peak resolution and method sensitivity for these challenging separations. Thermo Fisher will showcase the new EASY-Column within Thermo Scientific booth 2835 during Pittcon 2011, being held March 13-18, in Atlanta.

Simple and easy to use, the EASY-Column has precisely cut and polished ends, giving a perfect, zero dead-volume connection to the emitter and transfer lines. Each column is individually tested and subjected to rigorous inspection and quality control protocols. The EASY-Column sets a benchmark for easy-to-use compatibility, while providing the chromatographic performance required for demanding nanoscale LC applications.

For more information about the new Thermo Scientific EASY-Column, please visit Thermo Scientific booth 2835 at Pittcon 2011. Alternatively please visit the company article page.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.NanoLCNano LC is a nano scale liquid chromatography technique typically used for proteomic applications. The nano refers to the very low flow rate of the mobile phase in the system. The advantage of nanoLC is its high sensitivity. Often the system is integrated with a mass spectrometer in nano LC-MS or nano LC-MS/MS. When using nanoLC equipment consider column choice, software and accurate and precise flow rate control.

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Thermo Fisher Scientific Introduces Flexible, Adaptable Column for Nanoscale HPLC