Thermo Fisher Scientific Introduces Enhanced LC/MS Detection System

18 Jan 2007

Product news

Thermo Fisher Scientific Inc., the world leader in serving science, announces the release of the latest and most advanced version of its high speed single quadrupole LC/MS detection system, the Thermo Scientific MSQ Plus.

The MSQ Plus has been enhanced to feature fully automated system security, secure data integrity, built-in audit trails and electronic signatures and signoffs, enabling 21 CFR Part 11 compliance. Additionally, the MSQ Plus can be seamlessly integrated with the new Thermo Scientific High Speed LC system, Accela™. This configuration enables both conventional, as well as high speed LC separations with an MS detector, providing a unique, complete and efficient analytical solution for drug development and discovery, QA/QC, academic, food and beverage, government and research laboratories.

The new MSQ Plus utilizes the Thermo Scientific Xcalibur™ software platform for optimum security of data. Xcalibur works in conjunction with the Microsoft® Windows® XP to set and control permissions for access, provide electronic signatures, signoffs of results. Date and time-stamped audit trails ensure that all data and changes to the instrument are methodically stored in the secure environment.

The MSQ Plus provides unsurpassed performance and ruggedness while being extremely easy-to-use. Additionally, this highly sensitive instrument features the world’s most compact design and with its’ ultra fast data collection scan rates, it is ideal for high speed chromatography.

“The Thermo Scientific MSQ Plus provides extremely fast scan rates of up to 12,000 amu per second,” says Ray Chen, product manager for the MSQ Plus at Thermo Fisher Scientific. “This ensures ample data sampling rates of components from fast LC or U-HPLC systems to sensitively collect, characterize, and quantitate these data.”

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
Thermo Fisher Scientific Introduces Enhanced LC/MS Detection System