Thermo Fisher Scientific Introduces Automated Solution for Assay Ready Cell Culture

29 Jan 2007

Product news

Thermo Fisher Scientific Inc., the world leader in serving science, today unveiled its new Thermo Scientific Cell Growth and Discovery (CGD) WorkCell™, a fully enclosed, environmentally controlled automation solution designed for high capacity cell growth, supply and in-line image analysis.

Combining state-of–the-art software with sophisticated robotics, the CGD WorkCell is a turn-key system which can simultaneously handle multiple plate/flask formats and perform cell maintenance, colony selection and RNAi studies. The CGD WorkCell can significantly improve the quantity and quality of characterized cells, eliminating human error and improving data consistency.

The Thermo Scientific CGD WorkCell has been designed specifically for the growth and analysis of multiple cell lines and cultures. This high capacity system offers full level II HEPA containment with strategic ports for easy user access while still protecting cells from contamination, and users from potentially hazardous aerosols and vapors. Importantly, the CGD WorkCell can perform a wide variety of assays at the optimal point of cell growth and has extensive process flexibility to meet the culture and experimental demands of varying cell types. With the ability to accommodate multiple container formats, the CGD WorkCell can provide cells suitable for a variety of research needs, from cloning and transfection studies, to general cell line amplification in one system.

The new Thermo Scientific CGD WorkCell is powered by Celleste™ Software, and provides a user-friendly workflow management tool that can significantly improve laboratory operations and production. The Celleste Software turns complex automated multi-cell line schedules into simple task buttons and configures process-specific operations for ease-of-use. Users can dynamically schedule automated cell growth, manipulation and analytical procedures, tracking activities without actively managing complex cell growth programs. Additionally, the CGD WorkCell allows extensive method optimization and control monitoring. 24/7 operation enables long-term cell maintenance, providing alerts when cells are confluent and ready for use, and tracking reagents and consumable levels.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.RNA InterferenceRNA interference (RNAi) uses siRNA or miRNA for transcriptional silencing, gene knockdown and regulation of gene expression. RNAi requires chemical synthesis, introduction of DNA vectors into cells, an assay of RNAi effects and RNAi quantification or analysis. Consider target sequence selection, reagent preparation, controls, high specificity and effectiveness and low non-specific gene knockdown.
Thermo Fisher Scientific Introduces Automated Solution for Assay Ready Cell Culture