Thermo Fisher Scientific Forms Technology Alliance Partnership with the University of Birmingham, UK

28 Mar 2013
Sarah Thomas
Associate Editor

Product news

Thermo Fisher Scientific Inc., the world leader in serving science, has entered into a Technology Alliance Partner agreement with scientists at the University of Birmingham, UK, establishing a collaboration to accelerate research in high-resolution accurate mass (HRAM) and triple quadrupole liquid chromatography-mass spectrometry (LC-MS) for life science applications.

The alliance will focus on two research areas:
• Metabolomics, where the Thermo Fisher Scientific team will work with the laboratories of Professor Mark Viant and Dr. Warwick Dunn, to develop and test new hardware and software approaches for metabolite detection and identification for environmental and clinical research
• Proteomics, working with Dr Helen Cooper’s lab to exploit high resolution mass spectrometry and gas-phase ion chemistry for top-down and bottom-up analysis of proteins.

The Technology Alliance Partnership establishes a broad collaboration between Thermo Fisher Scientific and the University of Birmingham. It includes: engaging in research, sharing samples and data that could lead to development of better techniques, exchanging ideas for improving instrument and software performance, ongoing conversations about current technology issues, promoting the training of graduate students, and publishing new methodology and scientific advances.

Thermo Fisher’s Technology Alliance Partnership program is an ongoing initiative to drive innovation through the sharing of ideas and expertise between a number of academic research laboratories and the company.

“The University of Birmingham scientists share our drive to make the world healthier, cleaner and safer,” said Iain Mylchreest, vice president, research and development, Thermo Fisher Scientific. “We look forward to a very productive collaboration with this innovative, creative group for advancing metabolomic and proteomic research.”

“We are excited to become Thermo Fisher Scientific’s first Technology Alliance Partner within Europe,” said Professor Adam Tickell, the University’s pro vice chancellor for research and knowledge transfer. “We anticipate that innovations from this research will translate directly into improved healthcare and environmental diagnostics. We are particularly excited by Thermo Fisher’s commitment to supporting graduate research.”

The partnership builds upon the University of Birmingham’s Systems Science for Health initiative, which focuses on introducing a variety of life science technologies into clinical research. It follows almost a decade of collaboration between the two organizations.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Protein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.MetabolomicsMetabolomics is the study of small metabolites (the intermediates and products of metabolism). It involves the identification and quantification of cellular metabolites using analytical technologies such as GC, HPLC, NMR, and LC/MS.