Thermo Fisher Scientific Announces Introduction of New HPLC/UHPLC Column for Analysis of Challenging Glycans and Glycan Isomers

7 Feb 2014
Sarah Thomas
Associate Editor

Product news

Thermo Fisher Scientific is pleased to announce the introduction of new HPLC and UHPLC column, Thermo Scientific GlycanPac AXR-1 column, for glycan analysis. This new column offers extremely high-resolution separations based on charge, isomerism, and size and are designed to facilitate both high resolution glycan profile characterization and quantification.

“Until now, glycans isomers could not be separated by conventional HPLC,” said Ilze Birznieks, Product Marketing Manager for Biocolumns at Thermo Fisher. “This new column helps users achieve greater resolution of glycans using HPLC, providing easier profile characterization. This is useful for characterizing glycans from monoclonal antibodies being developed for therapeutics.”

The GlycanPac AXR-1 columns are designed for excellent resolution of labeled and unlabeled glycans, and are compatible with fluorescence and mass spectrometry detection methods.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.GlycansTherapeuticsTherapeutics are treatments designed to alleviate or cure diseases. These include pharmaceuticals, biologics, and gene therapies, which work by targeting specific disease mechanisms. Advances in personalized medicine and biologics offer new hope for patients with conditions that were previously difficult to treat. Browse our peer-reviewed product directory to find therapeutic solutions for various diseases; compare products, check user reviews, and get pricing directly from manufacturers.
Thermo Fisher Scientific Announces Introduction of New HPLC/UHPLC Column for Analysis of Challenging Glycans and Glycan Isomers