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Thermo Fisher Scientific and BIOCRATES Life Sciences Launch Industry’s First Kit for Comprehensive Metabolome Analysis

Thermo Fisher Scientific
6 Jun 2017
Weylan Kiam-Laine
Microbiologist

Product news

Thermo Fisher Scientific Inc., a world leader in serving science, and BIOCRATES Life Sciences AG, a global leader in metabolic phenotyping, have launched a ready-to-use kit for accurate and confident metabolic phenotyping on high-resolution mass spectrometry instruments. As part of a co-marketing agreement, the companies will jointly promote and market the combined use of the kit and Thermo Fisher’s Q Exactive high-resolution, accurate-mass (HRAM) platform of mass spectrometers.

The new BIOCRATES AbsoluteIDQ® p400 HR kit is the industry’s first, comprehensive kit for targeted metabolomics analysis, designed to help researchers efficiently unlock the complexity of the metabolome. Taking full advantage of the HRAM capabilities of the industry-leading Thermo Scientific Orbitrap mass spectrometry and BIOCRATES’ metabolic phenotyping technologies, the solution enables multiplexed, quantitative and standardized metabolome analysis at a substantial level of depth.

“This collaboration with BIOCRATES Life Sciences enables us to provide scientists with an important new solution for targeted metabolomics research,” said Andreas Huhmer, director, proteomics and metabolomics marketing, chromatography and mass spectrometry, Thermo Fisher. “Customers now have a standardized approach to quantitative and reproducible sample analysis to help them gain a deeper understanding of the metabolome.”

“The new AbsoluteIDQ® p400 HR Kit extends the highly regarded BIOCRATES metabolomics kit portfolio to take advantage of the multiplexed and quantitative power of Thermo Fisher’s Q Exactive HRAM technology,” said Dr. Therese Koal, head of R&D, BIOCRATES Life Sciences AG. “This will bring the potential for fast, efficient, quantitative metabolic phenotyping with inter-laboratory comparability to the proteomics and metabolomics communities to support metabolomics research and precision medicine opportunities.”

With the new kit, scientists can analyze up to 408 key metabolites, covering 11 central metabolite classes, using just 10 microliters of biofluidic sample volume. Supported by BIOCRATES MetIDQTM software, scientists can achieve automated workflow-controlled processing of up to 82 samples per kit, delivering outstanding longitudinal results, as well as inter-laboratory comparability.

During ASMS, Thermo Fisher and BIOCRATES will describe their collaboration through presentations, workshops and posters by notable scientists and industry experts. The new kit will be on display at the annual American Society of Mass Spectrometry (ASMS) conference (Thermo Fisher Booth 601 and BIOCRATES Booth 904), June 4-8, at the Indiana Convention Center and in the Thermo Fisher Hospitality Suite, White River Ballroom F-J, at the JW Marriott in Indianapolis.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.MetabolomicsMetabolomics is the study of small metabolites (the intermediates and products of metabolism). It involves the identification and quantification of cellular metabolites using analytical technologies such as GC, HPLC, NMR, and LC/MS.ASMSThe American Society for Mass Spectrometry (ASMS) is an organization dedicated to advancing the science and application of mass spectrometry. ASMS supports professionals through events, publications, and research initiatives, promoting innovation in areas like proteomics, metabolomics, and environmental analysis. Phenotypic ScreeningPhenotypic screening assesses cellular responses to compounds, enabling drug discovery and target identification. This technique is pivotal in finding effective treatments for complex diseases. Discover phenotypic screening platforms and tools with peer-reviewed comparisons and pricing in our directory.

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