NewsLife Sciences
The SensiQ Family of SPR Systems – New Surface Chemistries
5 Jun 2008Product news
ICx Technologies recently introduced a range of new chemistries to complement the existing planar COOH chemistries and gold only surfaces. These include the following:
- Biotin capture – This is a neutravidin-based planar surface designed to work with biotinylated proteins and oligos.
- Avidin capture – Another planar surface that takes advantage of the high affinity of the biotin-avidin complex, this surface utilizes biotin on the surface to capture avidin conjugated proteins.
- His-Tag Capture – This surface utilizes the Ni-NTA complex to capture His-tagged proteins for subsequent binding to biomolecules.
- Hydrophobic – This is especially well-suited for the immobilization of vesicles or membranes in the study of receptor protein binding interactions.
- High Capacity – Various three dimensional matrices are available for those studies that require surfaces with higher immobilization capacities for applications such as protein-small molecule interactions.
For more detailed information, visit the article webpage.
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BiosensorsBiosensors are devices used to detect an analyte using biological molecules specific to the analyte coupled to a detector. Biosensor instruments may be photometric, typically using surface plasma resonance (SPR), electrochemical or QCM (quartz crystal microbalance) biosensors. Biosensors should be selective, portable, robust and sensitive and have a fast response time. Systems may be manual or automated and usually have associated software.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.