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The Quad is Back: New Multi-Block Alpha Cycler 4 (PCRmax) Delivers Superior Value for High Quantity PCR

Bibby Scientific
15 Jun 2015
Lois Manton-O'Byrne, PhD
Executive Editor

Product news

PCRmax (a Bibby Scientific Company) has launched the Alpha Cycler 4, the only commercially available thermal cycler to offer four totally independent blocks. Capable of performing four totally independent runs simultaneously, the Alpha Cycler 4 delivers high throughput thermal cycling within a compact instrument footprint. With the ability to process high quantity protocols, thanks to its superior temperature control and accuracy, the Alpha Cycler 4 enhances the value of each PCR run while maximizing available laboratory space.

Performing high throughput PCR can be a costly and resource intensive process. The Alpha Cycler 4’s innovative ‘quad’ bay design and smart software features overcome these limitations by expediting PCR and easing operation, while delivering precise DNA amplification. Configurable in any combination of 96 to 384 well formats across its four bays, the Alpha Cycler 4 system provides a flexible platform for any sample scale and is ideally suited to high throughput, standard throughput and multiple user environments.

Advanced software features such as ‘Recently Used Programmes’ allows users to quickly access their most commonly used protocols without the need to navigate through folders to find them. A novel program wizard generates protocols based specifically from users primer sequence and template source, while individual logins ensure this time-saving feature is available to multiple users and secures user protocols to their specific login should they wish. Greater connectivity and real-time monitoring with a hand-held reporting device (such as a smart phone or tablet) then enables users to track their process to ensure that data quality never suffers. Finally active sample cooling delivers sharper and minimal non-specific amplification.

The Alpha Cycler 4 is part of the PCRmax commitment to maximize the value of PCR throughout the life science arena while maintaining the highest quality amplification.

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PCR and Thermal CyclingPolymerase chain reaction (PCR) kits and thermal cyclers are used for the in vitro amplification of DNA permitting subsequent analysis and experimental procedures. Explore a range of high-quality polymerase, primers and nucleotides or simplify your workflow with a PCR mastermix. Find reverse transcription PCR (RT-PCR) and cDNA synthesis kits for RNA products and libraries. Quantitatively measure the amplification of DNA with real-time PCR (qPCR) and droplet digital PCR (ddPCR) kits and systems, and discover automated PCR setup solutions to increase throughput. Alternative DNA amplification methods also include recombinase polymerase amplification (RPA) kits. Find the best PCR kits and thermal cyclers and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA AmplificationDNA Amplification is a technique used to amplify a single or multiple copies of DNA or mRNA by orders of magnitude. The most common method employed is PCR, but other options exist that eliminate the need for thermocycling.PCR AutomationPCR automation describes the process of using a thermocycler to complete the polymerase chain reaction (PCR) process quickly and efficiently.

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The Quad is Back: New Multi-Block Alpha Cycler 4 (PCRmax) Delivers Superior Value for High Quantity PCR