The Multifaceted Diode Array Detector AZURA® DAD 2.1L from KNAUER

22 Mar 2016
Lynsey Forsyth
Post Doc / Research Fellow

Product news

The KNAUER AZURA DAD 2.1L diode array detector with innovative cartridge flow cell design covers an extensive application range from nano to process scale liquid chromatography (LC).

By means of straightforward and swift flow cell exchange, this detector can be optimized within seconds for highly sensitive analytical UHPLC/HPLC or for in-line detection at high flow rates (> 10 L/min). State-of-the-art total reflection flow cells (LightGuide technology) are available for this device providing maximum light throughput with minimal peak dispersion. Flow cell types and materials are available for HPLC, biochromatography (FPLC) and for other flow-through applications.

Remote Flow Cells

With the aid of a world-first fiber optics adapter in cartridge design, the flow cell can be spatially separated from the device up to 10 m. Key applications of this remote flow cell technology include enhanced security for explosive, radioactive or toxic applications; detection at high temperatures (100 °C); and flexible flow cell installation. The latter can be useful to minimize system dead volume between column and detector or in multiple detector setups. Frontal access and improved safety features enable effortless lamp replacement for easy maintenance and short downtimes.

Flexibility of Control

The AZURA DAD 2.1L detector can be controlled with OpenLab® EZChrom Edition, ClarityChrom® and PurityChrom® Bio and even more software packages. Direct control is possible from an optional Mobile Control app for windows tablet or PC. Connection via LAN or analog signals allows easy integration into almost any LC system.

Key Features

  • Wavelength range 190 – 700 nm
  • 8 detection channels (digital)
  • 4 (analog)100 Hz max. data rate (digital), 12.5 Hz (analog)
  • Wide application range
  • High sensitivity
  • Remote flow cells available (fiber optics)
  • User-friendly and easy maintenance
  • Attractively priced

​Key Applications

  • High sensitivity UHPLC
  • HPLC
  • Purification LC, including (FPLC)
  • Safety-critical multi-wavelength detection
  • Flow-through applications (µL/min up to 10 L/min range)

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.NanoLCNano LC is a nano scale liquid chromatography technique typically used for proteomic applications. The nano refers to the very low flow rate of the mobile phase in the system. The advantage of nanoLC is its high sensitivity. Often the system is integrated with a mass spectrometer in nano LC-MS or nano LC-MS/MS. When using nanoLC equipment consider column choice, software and accurate and precise flow rate control.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.
The Multifaceted Diode Array Detector AZURA® DAD 2.1L from KNAUER