The Mouse Whole Genome siRNA Set V1.0 for accessible high-throughput RNAi screening

25 Apr 2006
Kerry Parker
CEO

Product news

The Mouse Whole Genome siRNA Set V1.0 is the latest addition to QIAGEN’s comprehensive range of solutions for high-throughput RNAi. The set comprises siRNAs targeting ~22,300 mouse genes. Innovative siRNA design ensures highly potent and specific siRNA. Flexible options include a range of scales and formats, and subsets for kinases, phosphatases, and GPCRs.

siRNAs in the Mouse Whole Genome siRNA Set are designed using the unique HiPerformance siRNA Design Algorithm, which combines novel neural-network–based design and stringent homology analysis. This combination generates siRNA which results in high target gene knockdown with minimal off-target effects.

The Mouse Whole Genome siRNA Set is provided with complete siRNA sequence disclosure at no extra cost. All rights to any invention or discovery developed by researchers using these sequences belong to the researcher, allowing complete freedom for discovery. For more information about the Mouse Whole Genome siRNA Set and other siRNA sets from QIAGEN, visit www.qiagen.com/siRNA.

Links

Tags

Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.RNA InterferenceRNA interference (RNAi) uses siRNA or miRNA for transcriptional silencing, gene knockdown and regulation of gene expression. RNAi requires chemical synthesis, introduction of DNA vectors into cells, an assay of RNAi effects and RNAi quantification or analysis. Consider target sequence selection, reagent preparation, controls, high specificity and effectiveness and low non-specific gene knockdown.