Syngene's G:BOX XR5 is Being Utilized at The University of Cambridge

10 Sept 2012

Product news

Syngene, a world-leading manufacturer of image analysis solutions, is delighted to announce that the G:BOX XR5 imaging system is now being used at the University of Cambridge. The G:BOX XR5 imaging system is being used to visualize and analyze DNA as part of a research program to understand the molecular mechanisms behind why the remyelination process fails in diseases such as Multiple Sclerosis (MS).

Scientists in the Neurosciences Group at the Department of Veterinary Medicine, part of the University of Cambridge are using a G:BOX XR5 system to accurately image gels of fluorescent dye stained PCR products derived from genes involved in the remyelination process. By studying these genes, the scientists hope to find a means of enhancing the repair of normally non-repairable clinical conditions such as MS.

Dr Chao Zhao Assistant Director of Research, in the Neurosciences Group says: “Our research focuses on the mechanism of remyelination of the central nervous system after demyelination. To do this we are trying to understand the molecular mechanism of why myelin repair fails in diseases such as MS and we use the G:BOX XR5 every day to visualize and sometimes analyze very small amounts of PCR products as part of this research.”

Dr Zhao continued: “We consistently get the results we want with our G:BOX XR5 so we are happy with the system for our DNA analysis work.”

Laura Sullivan, Syngene’s Divisional Manager said: “We are delighted to hear researchers at such a prestigious department in the university are using Syngene technology in this important program. Their work is testament to the fact that for DNA analysis, the G:BOX XR5 is a totally reliable and sensitive gel documentation system.”

G:BOX Chemi XRQ

Syngene

G:BOX Chemi XRQ is a cost-efficient chemiluminescence imaging and gel documentation system. For a laboratory that needs hassle-free chemiluminescent detection, as well as routine gel documentation, using the G:BOX Chemi XRQ’s powerful GeneSys software to switch between applications is simplicity itself.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Gel Doc / Image AnalysisGel documentation (gel doc) or gel imaging systems are used for the analysis of proteins, antibodies and nucleic acid immobilized in polyacrylamide or agarose gels, membranes or microarrays. Explore a range of a gel imaging systems, densitometers, scanners, transilluminators or UV lamp + CCD cameras for your image analysis solutions. Colorimetric, fluorescent and/or radioisotopic samples can be visualized and documented for further analysis. See gel doc / Image analysis software for quantitative 1D and 2D analysis of your samples. Find the best gel doc / image analysis products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Multiple SclerosisRemyelination
Syngene's G:BOX XR5 is Being Utilized at The University of Cambridge