Swift Biosciences Launches Accel-NGS™ 2S DNA Library Kit – Dramatically Reduces Sample Requirements for NGS Sample Prep

3 Mar 2014
Sarah Thomas
Associate Editor

Product news

Swift Biosciences, Inc. has announced the launch of the Accel-NGS™ 2S DNA Library Kit for Illumina Next Generation Sequencing (NGS) systems.

Incorporating patent-pending technology, the Swift “2S” kit provides linear yields from inputs ranging from 10 pg to 1 µg. PCR-free libraries can be produced from as little as 100 ng. Unlike other commercially available kits, exceptional quality and evenness of coverage are obtained even at very low levels of DNA input. The product is also is ideally suited for clinical samples such as FFPE tissues and plasma.

A single kit for varied DNA library needs

Accel-NGS 2S enables NGS laboratories to stock and use a single kit for their varied DNA library needs, ranging from high molecular weight DNA to limited quantity, damaged FFPE samples. In addition to whole genome sequencing, Accel-NGS 2S is also compatible with the leading hybridization capture products and is suitable for ChIP-Seq.

Built with usability in mind, the 2S protocol is readily automatable for those with high throughput applications. The wide dynamic range of input makes pre-library quantification optional, further streamlining workflow.

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DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Library GenerationLibrary generation refers to the construction of NGS libraries from RNA and DNA sources.FFPEFormalin-fixed paraffin-embedded (FFPE) tissues are commonly used in medical research, particularly in histology and cancer studies. The preservation process allows long-term storage of tissue samples for later analysis. Explore FFPE research products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.