Swift Biosciences Launch New Kit for Rapid NGS Sample Preparation

27 Feb 2013

Product news

Swift Biosciences, Inc. today announced the launch of the Accel-NGS™ DNA Library Kit, the first product in a new line of kits for Next Generation Sequencing (NGS) sample preparation.

NGS users can now produce PCR-free libraries with as little as 5 ng of input DNA. The highly efficient Swift adaptation technology eliminates the need for PCR, thereby minimizing base composition bias and fidelity issues while reducing the input requirement. The unique, two-step adaptation process also reduces adapter dimer formation to maximize sequencing output. Unlike other kits, the Accel-NGS DNA Library Kit does not require intact double-stranded DNA, making it ideal for FFPE and damaged samples.
The Accel-NGS DNA Library Kit protocol is fast, requiring only 75 minutes start-to-finish, and consists of 5 easy step, two of which are bead-based separations that eliminate the need for time-consuming, electrophoretic gel-based size selection. In addition, the streamlined Accel-NGS workflow can be easily automated.

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DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Library PreparationLibrary preparation is a critical step in sequencing workflows, where DNA or RNA samples are converted into libraries for high-throughput, next generation sequencing. This step ensures accurate results and minimizes biases. Explore library preparation kits in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.FFPEFormalin-fixed paraffin-embedded (FFPE) tissues are commonly used in medical research, particularly in histology and cancer studies. The preservation process allows long-term storage of tissue samples for later analysis. Explore FFPE research products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.
Swift Biosciences Launch New Kit for Rapid NGS Sample Preparation