SelectScience
Join Free
Accelerating Science
NewsLife Sciences

SurModics to Launch New BioFX TMB Extended Range HRP Microwell Substrate at AACC

SurModics, Inc.
20 Jun 2012
Sonia Nicholas
Managing Editor and Clinical Lead

Product news

SurModics has announced that it is to launch the new BioFX TMB Extended Range HRP Microwell Substrate (TMBX) at the AACC Lab Expo and Meeting next month. The TMBX substrate is the most recent addition to the SurModics family of TMB HRP Substrates.

Substrate choice is a critical consideration during assay development and can impact factors such as sensitivity, dynamic range and reproducibility. Use of TMBX in a quantitative assay can increase the assays upper limit of quantitation as well as maintaining the detection limits, and analytical sensitivity achieved with other substrates in our TMB family. Use of TMBX also improves the reproducibility of the assay through lower backgrounds and control of assay timing.

Although many research scientists view substrates as less critical to immunoassay performance than antibodies and other reagents, the right substrate can make a substantial contribution to the overall sensitivity of your assay. SurModics® offers a variety of colorimetric TMB substrates and complementary novel stop solutions available in both bulk and custom dispenses.

TMBX is a one-component substrate that requires no preparation prior to use.

You can visit SurModics at AACC 2012 Clinical Lab Expo, July 17-19, at the Los Angeles Convention Center in Los Angeles, CA - Booth 2246.

Links

SurModics, Inc.Company website

Tags

AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Cell Adhesion AssaysCell adhesion assays are used to quantitate attachment and analyze the molecular mechanisms for extracellular matrix adhesion, cell migration and sensitivity to inhibitors. Find the best cell adhesion assay equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ELISAEnzyme-linked immunosorbent assays (ELISA), also known as enzyme immunoassays (EIA), are used for the detection and quantification of proteins, peptides and antibodies in a sample. ELISA often comes in kit format, with pre-selected antibody pairs to detect specific proteins or biomarkers of diseases such as diabetes and obesity, or cardiovascular and neurological disorders. Detection is made possible with chemiluminescent, fluorescent or colorimetric substrates and detection instruments such as microplate / ELISA readers. Other kits available include: Enzyme-linked immunospot (ELISPOT) assays for the quantification of protein-producing cells and chemiluminescent immunoassays (CLIA) kits. Find the best ELISA kits and products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.AACCThe American Association for Clinical Chemistry (AACC) Annual Meeting and Clinical Lab Expo is the largest meeting for clinical laboratory professionals in the world. This year's meeting is being held in Atlanta, USA, July 26th-30th, 2015.

Related articles

SurModics to Launch New BioFX TMB Extended Range HRP Microwell Substrate at AACC