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Strategic Collaboration Between Aushon BioSystems and RDL Reference Laboratory to Advance Precision Medicine

Aushon BioSystems Inc.
11 Jul 2017
Abigail Berry
Administrator / Office Personnel

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Aushon BioSystems and RDL Reference Laboratory have announced that RDL has adopted Aushon’s CiraTM multiplex platform as part of a strategic collaboration between the two companies.

Under this relationship, RDL will utilize the highly sensitive Cira platform to simultaneously measure panels of protein biomarkers for early detection and measurement of changes in disease activity for several autoimmune conditions. In addition, RDL will offer Aushon’s full test menu as part of its newly expanded CRO services while developing its own novel diagnostic assays using the Aushon platform.

“Our collaboration with Aushon will advance our development of diagnostics with a high degree of precision and sensitivity in assays using multiple protein measurements”, said Dmitry Karayev, MD, Laboratory Director of RDL. “The ability to accurately and reproducibly measure small changes in multiple proteins opens up new possibilities for diagnostics in complex disease.”

Aushon’s Cira platform enables the simultaneous measurement of up to twelve biomarkers at ultrasensitive detection levels and has been validated to meet the performance requirements for use in clinical and biopharma research applications.

“We are delighted to collaborate with RDL and assist them as they expand their testing services, and in the development of new assays which can help patients live healthier lives,” said Susan Vogt, Chief Executive Officer of Aushon BioSystems, “We believe our platform will continue to play an important role in precision medicine advancing the use of biomarker profiles in diagnostics.”

Find more information about Aushon Biosystems here.

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Aushon BioSystems Inc.Company website

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ELISAEnzyme-linked immunosorbent assays (ELISA), also known as enzyme immunoassays (EIA), are used for the detection and quantification of proteins, peptides and antibodies in a sample. ELISA often comes in kit format, with pre-selected antibody pairs to detect specific proteins or biomarkers of diseases such as diabetes and obesity, or cardiovascular and neurological disorders. Detection is made possible with chemiluminescent, fluorescent or colorimetric substrates and detection instruments such as microplate / ELISA readers. Other kits available include: Enzyme-linked immunospot (ELISPOT) assays for the quantification of protein-producing cells and chemiluminescent immunoassays (CLIA) kits. Find the best ELISA kits and products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Companion DiagnosticsCompanion diagnostics are tests, often <i>in vitro</i>, that are used to determine whether a therapeutic product will be safe and effective for use on an individual. They also identify which patients will benefit most from them. Companion diagnostic tests are often developed in conjunction with the pharmaceutical industry.AutoimmunityProtein DetectionProtein detection techniques are essential for understanding protein expression, localization, and function. Methods such as western blotting, ELISA, and mass spectrometry are commonly used in research and diagnostics. Browse our peer-reviewed product directory to find the best tools for protein detection, compare products, check reviews, and get pricing directly from manufacturers.Assay DevelopmentThe process of proving an assay to be sensitive with respect to the target is known as assay development. The assay should be able to characterize novel compounds and measure the potency of these compounds against a validated biological target.Biomarker DiscoveryClinical biomarkers refer to substances related to known medical conditions that can be accurately measured <i>in vitro</i>. Biomarkers can be used to diagnose presence of a disease and indicate disease severity. The discovery of new biomarkers is incredibly valuable in the field of diagnostics.

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Strategic Collaboration Between Aushon BioSystems and RDL Reference Laboratory to Advance Precision Medicine