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SomaLogic to Launch Breakthrough Proteomic Technology at ELRIG ‘Companion Diagnostics’ Conference

ELRIG
23 Mar 2012
Sonia Nicholas
Managing Editor and Clinical Lead

Industry news

SomaLogic, Inc., has announced that it is to launch SomaSciences in the United Kingdom, making SomaLogic’s breakthrough proteomic technology available to researchers across the country.The SomaSciences launch will take place at the ELRIG – ‘Companion Diagnostics’ Conference on May 1, 2012 at The Belfry, Oxford.

The measurement of proteins provides the most immediate, real-time assessment of the state of health and disease in individual patients. Unfortunately the ability to accurately identify and measure the thousands of proteins present in small amounts of biological sample, in a high-throughput and wide-ranging manner, has proven to be technologically unfeasible.


SomaLogic’s proprietary SOMAscanTM proteomic assay overcomes many of the limitations of current technologies and provides a “one stop shop” for the entire process from basic biomarker discovery to validated companion diagnostic. The SOMAscan technology also gives unprecedented protein biomarker support for drug discovery and development, including target discovery and validation, mechanism of action, prediction of efficacy, patient stratification, and drug response monitoring.

Steven Williams, M.D., Ph.D., Chief Medical Officer of SomaLogic, will present the company’s technology in a talk at the ELRIG ‘Companion Diagnostics’ Conference entitled:

“Unlocking protein biomarker discovery for diagnostics and therapeutics; Rapid translation to diagnostic products”

“We are delighted that this is the first formal European availability of our technology,” said Dr. Williams. “We look forward to building on our current strong collaborations in the UK and establishing new ones that will create additional opportunities for building transformative health care products.”


More information about SomaLogic and its SOMAscan technology can be found at www.somalogic.com.

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ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Medicinal ChemistryMedicinal chemistry is a broad discipline encompassing the design, identification, synthesis and development of chemicals in drug discovery. It includes a number of techniques covering structural biology, synthetic chemistry and molecular biology. Technologies used in medicinal chemistry include ADME, lab-on-a-chip, high content screening and assay assembly.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Companion DiagnosticsCompanion diagnostics are tests, often <i>in vitro</i>, that are used to determine whether a therapeutic product will be safe and effective for use on an individual. They also identify which patients will benefit most from them. Companion diagnostic tests are often developed in conjunction with the pharmaceutical industry.ELRIG

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