Sigma-Aldrich to Showcase the New Prestige Antibodies™ and Universal Proteomics Standards at HUPO 2008, Booth #026

20 Jul 2008

Product news

Visit us at booth # 026 to learn about our Prestige Antibodies and Universal Proteomics Standards. Prestige Antibodies offer significant value to the research community. Each antibody is highly validated for specificity and accompanied by over 500 immunohistochemical images, which are publicly accessible through Human Protein Atlas. All Prestige Antibodies are tested in multiple assurance steps to ensure they are the most specific products on the market.

Sigma also now offers both the Universal Proteomics Standard (UPS1) and the Proteomics Dynamic Range Standard (UPS2) as complex, well-characterized reference standards for mass spectrometry. These standards offer the same 48 human proteins in an equimolar and dynamic range format.

Sigma-Aldrich is a leading Life Science and High Technology company since 1945. Through SIGMA® Life Science, we have developed tools enabling researchers to accelerate discovery across the entire drug development research workflow including RNAi and sample prep platforms. We offer one of the broadest selections of cell biology reagents, including assay kits, small molecules, and antibodies highlighting our Prestige Antibodies portfolio.

See it all at booth # 026 or visit the article webpage for more information.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.RNA InterferenceRNA interference (RNAi) uses siRNA or miRNA for transcriptional silencing, gene knockdown and regulation of gene expression. RNAi requires chemical synthesis, introduction of DNA vectors into cells, an assay of RNAi effects and RNAi quantification or analysis. Consider target sequence selection, reagent preparation, controls, high specificity and effectiveness and low non-specific gene knockdown.