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Siemens Healthcare Diagnostics Introduces ADVIA Centaur HBsAgII

Siemens Healthineers
2 Jun 2011
bridget bridget
Laboratory Director

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Siemens Healthcare Diagnostics has introduced its second generation in-vitro immunoassay for the qualitative detection of Hepatitis B surface antigen (HBsAg) in human serum and plasma (EDTA, heparin, citrate) using the ADVIA Centaur® and ADVIA Centaur® XP systems.

“The new ADVIA Centaur HBsAgII assay offers leading analytical and clinical sensitivity to common HBsAg subtypes, resistance to HBsAg a-determinant mutations and excellent specificity, combined with all the productivity benefits of ADVIA Centaur immunoassay systems,” states Sarah Holt, Marketing Manager for Infectious Diseases at Siemens Healthcare Diagnostics.

The new HBsAgII assay will replace the existing HBsAg assay on the ADVIA Centaur systems. It can be used in conjunction with other serological and clinical information to diagnose individuals with acute or chronic Hepatitis B infection. The assay may also be used to screen for Hepatitis B infection in pregnant women to identify neonates at risk of acquiring Hepatitis B during the perinatal period.

Currently two billion people worldwide are infected with the Hepatitis B Virus (HBV) and an estimated 600,000 people die each year due to acute or chronic consequences of this disease especially in Asia and Africa.* It can be easily treated and healthy adults that are infected can recover with the result of lifelong immunity. Carriers of HBV can remain highly infectious and are a potential source of new infections. The chronically infected may suffer serious health consequences such as high risk of liver cirrhosis, liver cancer and may require a liver transplant as a last resort.

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HematologyIn Haematology / Hematology, complete blood cell counts (or full blood counts) are obtained using automated blood count analyzers to enumerate blood cell types.  Hematology also encompasses haemostasis and coagulation, thrombophilia and hemophilia, plasma viscosity and ESR analysis, hemoglobinopathies, cell morphology and haematinic measurement.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Point-of-CarePoint-of-Care Testing (POCT) or Near Patient Testing (NPT) products are available for urine, blood and other clinical chemistry analyses. POCT includes: blood glucose testing, blood gas and electrolytes analysis, rapid coagulation testing (PT / INR), rapid cardiac markers diagnostics, drugs of abuse screening, urine strips testing, pregnancy testing, fecal occult blood analysis, food pathogens screening, hemoglobin diagnostics, infectious disease testing and cholesterol screening.Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.

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Siemens Healthcare Diagnostics Introduces ADVIA Centaur HBsAgII