Shimadzu’s New MALDI-7090™ TOF-TOF Mass Spectrometer Combines High Throughput, High Resolution and High-energy for the Ultimate in Tandem MS Capabilities

Shimadzu introduces the new MALDI-7090™ MALDI TOF-TOF mass spectrometer targeted for proteomics and tissue imaging research. The combination of Shimadzu’s extensive MALDI-TOF-TOF expertise with novel patented technology provides the MALDI-7090 with ultimate capabilities for identification and structural characterization of biomolecules.

Innovative technology incorporated into the MALDI-7090, such as ASDF™- Axial Spatial Distribution Focusing, delivers market-leading high-resolution MALDI MS/MS for accurate compound characterization. This, in combination with proprietary solid-state laser technology, true 2 kHz acquisition speed in all modes (MS and MS/MS), an integrated 10-plate loader and newly designed MALDI Solutions™ software, sets a new benchmark in MALDI TOF-TOF design.

“The 2 kHz laser speed and high MS/MS resolution in the MALDI-7090 has accelerated our research in proteomics analysis for protein complex and histone modification using LC-MALDI,” said Takeshi Kawamura, assistant professor from RCAST, University of Tokyo.

The 20 keV high-energy CID capability of the MALDI-7090 efficiently produces additional fragment ions to further enhance characterization. “High-energy CID is the only way to locate double bonds in compounds containing fatty acids without any derivatization, for example triglycerides in plant oils used as food or corcins (color responsible structures) isolated in saffron,” said Günter Allmaier, professor from the Technical University of Vienna, citing the value of the MALDI-7090’s high-energy CID and high-resolution capabilities. “Data interpretation for structure elucidation of such high-energy CID spectra without isotopic resolved fragment ions is very hard to achieve.”

Comprising a powerful range of tools for method development, acquisition, data processing and interpretation, MALDI Solutions software allows automatic and manual control of the MALDI-7090 and has been designed to provide a flexible platform in the hands of both novice and expert users. Targeted software modules within MALDI Solutions address a wide variety of research applications including proteomics and tissue imaging.

“We are very proud to announce the release of the MALDI-7090 at ASMS 2013,” said Kozo Shimazu, managing director of Kratos Analytical, a wholly owned subsidiary of Shimadzu Corporation. “This newly designed MALDI TOF-TOF mass spectrometer broadens the Shimadzu MALDI product portfolio into the high-performance, high-throughput research field. The perfect complement to our AXIMA range of MALDI TOF and MALDI-QIT TOF instruments, the MALDI-7090 offers ultimate sample throughput with high-energy CID and high-resolution MS/MS. This introduction forms an integral part of Shimadzu’s comprehensive range of LCMS, GCMS and MALDI TOF mass spectrometers.”