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Shimadzu's new LC-MS/MS improves workflow efficiency and maximizes laboratory output

Shimadzu Corporation

The LCMS-8060NX includes artificial intelligence functions and a variety of other features to boost productivity

3 Jun 2020
Diane Li
Assistant Editor

Product news

Shimadzu Scientific Instruments (SSI) has introduced the LCMS-8060NX triple quadrupole liquid chromatograph mass spectrometer (LC-MS/MS). The culmination of a decade of triple quad engineering, this new instrument features world-class sensitivity and acquisition speeds, increased robustness to minimize downtime, unparalleled ease of use for greater workflow efficiency, and analytical intelligence functions to maximize laboratory output.

Newly developed ion focus lenses in the state-of-the-art integrated electrospray probe propel ions into the LCMS-8060NX with the greatest of efficiency. Neutral particles are expelled to reduce noise and provide the highest stability. A new heat assist design increases desolvation efficiency and promotes superior ionization of a wide range of compounds. Furthermore, the system's unique UFsweeper technology effectively sweeps ions from the collision cell without deceleration, maintaining high-sensitivity analysis even at high acquisition speeds.

The LCMS-8060NX employs new ion guides, the UF-Qarray II and the UF-Lens II, to increase robustness while maintaining high ion transmission efficiency. Improved robustness means higher laboratory throughput as maintenance interval times increase. Further maximizing productivity, consumable parts like the ESI spray needle and the inlet desolvation line (DL) can be changed quickly and easily without breaking vacuum.

Designed for easy operation, the LCMS-8060NX incorporates optimized parameters based on AI research that enable high sensitivity without manual optimization. Features such as automated start-up and shutdown (with LabSolutions Connect MRM) enable unattended operation. Combining the MS with the new Nexera UHPLC 40 series provides multiple analytical intelligence functions to further increase the efficiency of the overall workflow.

To complement the LCMS-8060NX, SSI also introduces updated LabSolutions LCMS workstation software for total operator support, from analysis to data processing. The LabSolutions Connect/LabSolutions Insight platform supports the entire analysis workflow, including project file management, optimization of MRM and interface parameters, efficient verification of quantitative results, simple method and batch creation and verification of quantitative results.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Lab EssentialsLab essentials include laboratory consumables that are vital to the operation of all laboratories.ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.

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Shimadzu's new LC-MS/MS improves workflow efficiency and maximizes laboratory output