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Shimadzu’s GCMS Smart Database Series Simplifies GC-MS/MS Method Development

Shimadzu Corporation
24 Jun 2015
Chelsie Phillips
Temporary Editorial Assistant

Product news

Shimadzu Scientific Instruments have announced the release of its new GCMS Smart Database Series. The series is comprised of separate databases for analyzing pesticides, forensic toxicological substances, metabolites and environmental pollutants. Hundreds of related compounds with optimized transitions and collision energies, CAS registry numbers and retention indices (RI) are included within each database. The software series eliminates the need to configure complicated analysis conditions as simultaneous high-sensitivity analysis of samples using GC-MS/MS is supported.

Smart MRMTM technology enables automated creation of fully optimized multiple reaction monitoring (MRM) and Scan/MRM methods with the push of a button. This saves valuable time and effort associated with manually configuring measurement settings for multi-component batch analysis. Since retention indices are registered for all the components, users can quickly update retention times via the AART (Automatic Adjustment of Retention Time) function.

As part of the series, the Smart Metabolites Database is currently the world’s only commercial database for GC-MS/MS analysis of metabolomics. It is optimal for analyzing metabolites in biological samples. The database contains MRM transitions for 475 metabolites commonly found in samples such as blood, urine and cellular material.

The Smart Pesticides Database is ideal for analyzing residual pesticides in complex matrices. The database is registered with 477 components and 2,675 MRM transitions.

The Smart Forensic Database is registered with a total of 201 forensic toxicological substances and includes 1,200 MRM transitions. Categories of compounds include drugs of abuse, psychopathic drugs, general drugs, pesticides and rodenticides.

The Smart Environmental Database features 362 native compounds and 148 isotopically labeled compounds to support the analysis of environmental pollutants. Ideal applications for this database include analysis of organic compounds such as brominated flame retardants, PCBs, PAHs, PCDD/PCDF, and organochlorine pesticides in sediment, water, foodstuff and animal feed.

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ADME-ToxicologyADME-toxicology (ADME-Tox) studies are used in pharmacology and pharmacokinetics to assess the activity/toxicity of drugs <i>in vivo</i> or <i>in vitro</i>. Find bioassays for absorption, distribution, metabolism, and excretion of drug molecules including cytotoxicity, transporter/permeability, metabolism and activity assays as well as hepatocytes and cell lines for ADME. Find the best ADME-toxicology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Environmental Monitoring and TestingEnvironmental monitoring and testing uses handheld portable analyzers, kits, spectrometers or chromatography systems for air, water, soil, food and other sample testing. Useful features of analyzers such as BOD and COD include portability, easy calibration, automation and sensitivity.  Environmental test kits for pH, water, moisture, etc, should be accurate, sensitive, reliable, fast and easy to use.Toxicology / Drugs of Abuse TestingToxicology and Drugs of Abuse Testing is the investigation into toxic and illegal substances found at the scene of a crime or from a suspect and / or victim associated with a scene of a crime. Analyzers, immunoassays and drugs of abuse test kits and presumptive test kits are an essential aspect of toxicology investigation.GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.MetabolitesMetabolites are the intermediate and end products of metabolism. Analyzing metabolites offers insight into cellular processes and disease mechanisms and is critical in fields like pharmacology, toxicology, and diagnostics. Explore our peer-reviewed product directory to find the best tools for metabolite analysis, compare products, check reviews, and get pricing directly from manufacturers.MetabolomicsMetabolomics is the study of small metabolites (the intermediates and products of metabolism). It involves the identification and quantification of cellular metabolites using analytical technologies such as GC, HPLC, NMR, and LC/MS.PesticidesPesticides are used to protect crops from diseases, pests and unwanted plants. They are classed as persistent organic pollutants (POPs) and can be harmful to humans. The Environmental Protection Agency (EPA) currently regulates the use of pesticides in the USA. Data LoggingMRMEnvironmental ForensicsEnvironmental AnalysisEnvironmental analysis describes a variety of tests that determine the effect of chemicals, processes and particulates such as persistent organic pollutants (POPs) have on the environment.Forensic InvestigationForensic investigation is a diverse collection of scientific techniques and methods for the identification and characterization of chemicals relating to crime scene investigations.Persistent Organic PollutantsDatabase

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Shimadzu’s GCMS Smart Database Series Simplifies GC-MS/MS Method Development