Shimadzu Introduces Noviplex™ Cards for Accelerated Blood Plasma Collection and Disease Analysis

4 Mar 2014
Sarah Thomas
Associate Editor

Product news

Shimadzu Scientific Instruments (SSI) has introduced the Noviplex™ Next Generation Plasma Sample Collection tool. Noviplex Cards allow for rapid collection of a volumetric sample of plasma from an unmeasured amount of whole blood within minutes. The technology is ideal for use with LC-MS/MS analysis.

Noviplex Cards offer significant advantages for laboratory and medical professionals, accelerating analysis and simplifying blood collection by eliminating the need for phlebotomy, syringes and glass collection tubes.

Lab-free sample preparation

“Noviplex technology enables lab-free sample preparation, and the convenient ‘lab-on-a-card’ format rapidly generates plasma for LC-MS/MS analysis,” said Scott Kuzdzal, PhD, life science business unit manager at SSI. “This will greatly simplify collection and processing in medical clinics, labs and hospitals.”

Generate plasma from 20 to 75 μL of whole blood

Shimadzu partnered with Novilytic Laboratories to offer Noviplex Cards. The technology allows plasma generation from a finger-stick as opposed to traditional methods of blood collection and preparation. Plasma can be generated from specimen volumes ranging from 20 to 75 μL of whole blood. The technology offers a single-step, solid-phase method for sample preparation and analyte extraction. Noviplex accelerates processes by eliminating refrigeration, centrifugation solvent extraction and evaporation.

Accelerate disease marker analysis

“Next-generation Novilytic Laboratory advances in sample collection and preparation vastly accelerate disease marker analysis and enable a paradigm change in clinical chemistry, wellness monitoring and medicine,” said Fred Regnier, PhD, Professor Emeritus, John H. Law Distinguished Professor of Chemistry, Purdue University, and a co-founder of Novilytic Laboratories.

Noviplex also provides exceptional reproducibility independent of hematocrit, 99 percent removal of red blood cells, and rapid sample preparation for MS-based analysis while maintaining assay reproducibility and selectivity.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.HematologyIn Haematology / Hematology, complete blood cell counts (or full blood counts) are obtained using automated blood count analyzers to enumerate blood cell types.  Hematology also encompasses haemostasis and coagulation, thrombophilia and hemophilia, plasma viscosity and ESR analysis, hemoglobinopathies, cell morphology and haematinic measurement.Blood CollectionPlasmaHuman PlasmaHuman plasma is the liquid component of blood, which carries blood components - nutrients, hormones, proteins, and waste - throughout the body. Plasma-based studies provide insights into biomarkers, immune responses, and disease mechanisms. Compare plasma handling tools and systems in our peer-reviewed product directory.
Shimadzu Introduces Noviplex™ Cards for Accelerated Blood Plasma Collection and Disease Analysis