Selective binding and PCR clean-up with Sera-Mag Select

Automatable, magnetic bead-based, ready-made reagents based on solid phase reversible immobilization technology

27 Apr 2020
Edward Carter
Publishing / Media

Product news

Running a sequence through an instrument is expensive and time-consuming. Unreliable PCR clean-up and size selection can negatively affect productivity and credibility.

Sera-Mag Select is an automation-friendly, ready-made reagent based on the well-known solid-phase reversible immobilization technology. It combines the binding characteristics of Sera-Mag Carboxyl Speedbeads with an optimized binding solution in a ready-to-use formulation.

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Ideally used for selective binding of DNA fragments for applications such as next-generation sequencing (NGS) and PCR reaction clean-up, Sera-Mag Select promises to deliver reliable results and consistent performance – all at a competitive price.

  • Tight distribution in size selection for high yield recovery of specific fragment sizes.
  • DNA of 100 bp size or greater can be reliably recovered and the DNA size range isolated can be tailored to suit the user’s end requirements by adjusting the amount of reagent that is mixed with a fixed volume of sample.
  • Uses the same protocols as existing reagents so can be directly integrated into existing workflows with minimal disruption and allows a single reagent to be used for both PCR clean-up and size selection.
  • Easily control what size DNA is retained or eliminated by adding various ratios of Sera-Mag Select to your sample. This enables NGS library and PCR fragment clean-up, as well as dual size selection of libraries.

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Selective binding and PCR clean-up with Sera-Mag Select