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See the Advanced SpectraMax<sup>®</sup> M5e Microplate Reader from MDS Analytical Technologies at AACR 2008 in Booth 1617

Molecular Devices®
13 Apr 2008

Product news

MDS Analytical Technologies will feature its advanced SpectraMax® M5e multimode microplate reader at AACR 2008 in Booth #1617. This highly sensitive, tunable monochromators-based system provides integrated filter optics certified to run HTRF®, LanthaScreen™, and IMAP® microplate assays. Users can choose any wavelength between 250 nm and 850 nm and select the best-suited parameters for their assays. Fluorescence, TRF, FP, absorbance, and luminescence detection modes with temperature control (up to 600C) can run cell viability and proliferation, kinase, reporter gene, ELISA, nucleic acid and protein quantification, as well as enzymatic assays.

You can also see the following high performance bioanalytical measurement systems on display in Molecular Devices' (now a part of MDS Analytical Technologies) booth #1617:

  • NEW! CellKey™ 384 System—high-throughput, label-free, cell-based assay technology is now in 384-well format.
  • AquaMax™ System—liquid handling system provides precise dispensing and thorough washing, all in one instrument.
  • IonWorks™ Quattro System—turnkey automated patch-clamp system for primary and secondary screening with Population Patch Clamp technology.
  • FLIPRTETRA® System with Aequorin Option—reliable, flexible high-throughput screening solution to monitor GPCRs and ion channels. The system performs fluorescent and luminescent assays including Aequorin.
  • ImageXpressULTRA™ System—true point-scanning confocal optics and laser-based illumination.

To learn more and speak with our product experts, please visit our booth #1617.

Links

Molecular Devices®Company website

Tags

High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.

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See the Advanced SpectraMax<sup>®</sup> M5e Microplate Reader from MDS Analytical Technologies at AACR 2008 in Booth 1617