Renishaw introduces breakthrough time-resolved Raman spectroscopy integration

TRRS leverages the faster interaction time of Raman scattering to distinguish the Raman signal from the fluorescence background

16 Jan 2026

Product news

inVia™ confocal Raman microscope

inVia™ confocal Raman microscope

Renishaw has launched its latest innovation in Raman spectroscopy: the integration of time-resolved Raman spectroscopy (TRRS) into its inVia™ confocal Raman microscope. This cutting-edge technique enables researchers and engineers to overcome the long-standing challenge of sample fluorescence, unlocking high-quality Raman spectra from samples previously deemed unmeasurable.

TRRS leverages the rapid interaction time of Raman scattered photons — occurring within picoseconds of laser excitation — to distinguish them from the slower fluorescence background. This technique employs a variety of state-of-the-art technological innovations including a newly developed single-photon avalanche diode (SPAD) array detector, designed and manufactured by Singular Photonics.

This sensor utilizes advanced CMOS SPAD technology and can detect individual photons and record their arrival time with 50 picosecond temporal precision. Historically, isolating the Raman photons from the fluorescence background has been complex, but with Renishaw’s proprietary algorithms, extracting Raman data is automatic, ensuring this advanced technique is accessible to a wide range of users.

The TRRS integration enables Raman analysis of a variety of challenging samples, such as food, oils and lubricants, and polymers (including those containing pigments and dyes).

Renishaw and Singular Photonics have been developing this technology, with multiple associated patents, for several years. This latest integration marks a significant milestone in Raman spectroscopy, making it possible to unlock chemical and structural information from real-world samples with high background fluorescence that were previously inaccessible.

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inVia Raman microscope

Renishaw plc.

Since being launched, the Renishaw inVia Raman microscope has become the world's best selling research Raman system. The inVia Raman microscope combines simplicity of operation with the high performance and unparalleled flexibility for which Renishaw Raman systems are renowned. inVia Raman microscopes are high-sensitivity systems with integrated research grade microscopes, enabling high resolution confocal measurements. inVia Raman microscopes support multiple lasers, with automatic software switching of excitation wavelength.

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Raman SpectroscopyRaman spectroscopy is used to discern the vibrational and rotational states of molecules and hence the chemical composition of a sample by measuring the inelastic scattering of monochromatic light. Explore a range of Raman spectrometers, including handheld/portable Raman spectrometers for QC/QA labs and in situ spectrometers for processes. Conduct Raman imaging for microanalysis of mixed samples using a Raman microscope. Raman spectrographs are also available. Find the best Raman spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Electron MicroscopyElectron microscopes (EM) are used to create high-resolution images of samples at the nanoscale by means of an accelerated beam of electrons as a source of illumination. Types of electron microscope include scanning electron microscopes (SEM), transmission electron microscopes (TEM), scanning transmission electron microscopes (STEM) and cryo-electron microscopes. Focused ion beam (FIB) microscopes are useful for modifying or milling a sample surface with nanometer precision, as well as imaging. Find the best electron microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.FluorescenceThe emission of fluorescence occurs when a photon of energy is supplied to a fluorescent chemical compound by an external source, causing it to become excited. Fluorescence can be detected and measured for different purposes using microplate readers, fluorescence microscopes, fluorescence scanners, and flow cytometers.