SelectScience
Join Free
Accelerating Science
NewsSpectroscopy

Register Now for our Free Environmental Analysis Webinar

SelectScience

Discover analytical methods for screening of pharmaceuticals in environmental samples

15 Apr 2015
Lois Manton-O'Byrne, PhD
Executive Editor

Expert insights

Dr Leon Barron, of King's College London, will present this exclusive webinar

The true breadth of pharmaceutical and illicit drug residue contamination within an aqueous environment can often be underestimated, due to the use of targeted analytical approaches for just a small number of compounds. The use of high resolution mass spectrometry (HRMS) as an analytical tool helps to address this issue, but chromatographic retention time is still often required to confirm drug occurrence. There may potentially be thousands of compounds that do not have reference standards commercially available to make a confirmation.

In this webinar, Dr Leon Barron, Lecturer in Forensic Science for the Analytical and Environmental Science Division at King's College London, will discuss:

  • How Liquid Chromatography High Resolution Mass Spectrometry (LC-HRMS) enables semi-targeted screening of waste- and river water.
  • How post-acquisition data-mining tools help manage delivery of large data sets.
  • How to use intelligent approaches to predict chromatographic retention time without the use of analytical reference standards.

Don’t miss out on this informative event, to be held at 08:00 PDT / 11:00 EDT / 16:00 BST / 17:00 CEST, April 23 2015! Click here to register for the webinar and Q&A session, and if you can't make the date, register to watch it on-demand.

Register Now >>

Links

SelectScienceCompany website

Tags

UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Environmental Monitoring and TestingEnvironmental monitoring and testing uses handheld portable analyzers, kits, spectrometers or chromatography systems for air, water, soil, food and other sample testing. Useful features of analyzers such as BOD and COD include portability, easy calibration, automation and sensitivity.  Environmental test kits for pH, water, moisture, etc, should be accurate, sensitive, reliable, fast and easy to use.Waste WaterDrugs of AbuseA drug of abuse is a drug that has been taken for non-medical purposes. Such drugs can have mind-altering effects, with some causing dependence and addiction.Environmental ContaminationContaminants in the environment are harmful chemicals that are present in the air, land and water. These include pesticides, pharmaceuticals, persistent organic pollutants (POPs) and many more.PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.

Related articles