Reducing productivity bottlenecks in post synthesis work-up

28 Jan 2008

Product news

Simple and convenient, the Carousel Work-Up Station from Radleys is proven to reduce post synthesis bottlenecks.

Designed to make post synthesis work-up and purification quick and easy, the Carousel Work-Up Station facilitates parallel or sequential work-up of up to 12 samples, using filtration, phase separation, liquid/liquid extraction or SPE techniques. The innovative system is designed for use with the 12 position Carousel Reaction Station or similar parallel synthesisers.

Compact the Carousel Work-Up Station accepts up to 12 x 70ml columns loaded into one of two identical stackable racks. This enables parallel and/or sequential work-up of 12 samples and collection of product into a lower rack with Carousel Reaction Tubes or standard 1 inch boiling tubes.

The unique design uses no taps, valves or drip needles, making assembly and operation fast and simple. The system may be used under gravity or with the innovative SpeedFlow Booster allowing precise individual control of solvent flow within each column.

Ergonomically designed the Carousel Work-up station uses lightweight aluminium racks that are both easy to load and exceptionally stable providing good access and visibility to all the columns and tubes. Identical racks lock together for ease of operation or transportation from location to location. For enhancing post synthesis work-up further the system provides option for a third rack above the second rack for sequential work-up.

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Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.FiltrationFiltration and microfiltration are used to separate solids, particulates or large molecules from fluids (liquid or gases) in order to purify the filtrate. Explore a range of filter formats, including filter paper, plates and membranes for your separation needs. While larger particulates may be separated by gravity filtration, smaller particulates may require additional force for timely separation. Microfiltration equipment includes vacuum filters, as well as positive pressure, crossflow and centrifugal filtration devices. Find the best filtration products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Medicinal ChemistryMedicinal chemistry is a broad discipline encompassing the design, identification, synthesis and development of chemicals in drug discovery. It includes a number of techniques covering structural biology, synthetic chemistry and molecular biology. Technologies used in medicinal chemistry include ADME, lab-on-a-chip, high content screening and assay assembly.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Solid-Phase ExtractionSolid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.