Recent Innovations in NMR Applications

9 Dec 2014
Lois Manton-O'Byrne, PhD
Executive Editor

AVANCE 1000

Bruker BioSpin launches a breakthrough one Gigahertz Ultra-High Field AVANCE 1000 MHz NMR spectrometer. Incorporating a record-breaking 23.5 Tesla standard-bore (54 mm) superconducting NMR magnet, the AVANCE 1000 MHz NMR spectrometer, brings one Gigahertz technology to NMR research. AVANCE 1000 MHz NMR Spectrometer with the first 1 GHz CryoProbe installedThe high field strength and high field stability in combination with the first 5 mm triple-resonance CryoProbe enables unique 1 GHz NMR applications. Bruker is proud to be able to equip researchers with such an outstanding instrument that will helpto push the frontiers in biochemistry, structural biology and other molecular research. The first Avance 1000 system was delivered to the new ‘Centre de RMN à Très Hauts Champs’ in Lyon, France in July 2009. Bruker BioSpin has successfully completed installation in November 2009. The AVANCE 1000 now offers unparalleled research opportunities, both to CRMN and to other National and European scientists who will access the unique facility.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. NMR and EPR SpectroscopyNuclear magnetic resonance (NMR) spectroscopy is used to resolve the local chemical environment of atomic nuclei with spin, revealing information on molecular structure, dynamic processes and chemical reactions of organic molecules, from proteins to synthetics. Electron paramagnetic resonance (EPR) also known as electron spin resonance (ESR) spectroscopy is used to detect and quantify paramagnetic species in a sample, including free radicals as transition metal ions. By immersing the sample in a strong magnetic field, both NMR and EPR spectrometers probe the sample with either radio waves or microwaves respectively. A range of benchtop, solid-state and time domain NMR spectrometers & EPR spectrometers are available, as well as NMR tubes, NMR solvents, software, coils, and magnets. Find the best NMR & EPR equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.MetabonomicsMetabolomicsMetabolomics is the study of small metabolites (the intermediates and products of metabolism). It involves the identification and quantification of cellular metabolites using analytical technologies such as GC, HPLC, NMR, and LC/MS.Precision MedicinePrecision medicine refers to the idea of customized healthcare, where medical decisions and treatments are tailored to the individual patient. Molecular diagnostics, companion diagnostics and Next Generation Sequencing (NGS) play a pivotal role in this approach.