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Rapidly acquire quantitative data from cell-based assays

EVIDENT
11 Dec 2019
Laura Sisman
Administrator / Office Personnel

Product news

Olympus has announced the US launch of the scanR high-content screening (HCS) station, a cell imaging solution that utilizes artificial intelligence (AI) to enable next-generation biological research.

The platform combines the modularity and flexibility of a microscope-based setup with the automation, speed, throughput, and reproducibility of an HCS station.

AI Meets High-Content Screening

The Olympus scanR HCS station uses the power of AI to carry out groundbreaking analyses of cells that, until recently, seemed impossible to do. Olympus’ self-learning microscopy technology reduces photobleaching and improves acquisition speed, measurement sensitivity, and accuracy, facilitating longer observations with reduced influence on cell viability.

The Power of Deep Learning

The system acquires pairs of images that are processed by the software to generate an image analysis model. Olympus’ optimized deep-learning technology, which is based on a dedicated convolutional neural network architecture, provides powerful and flexible learned analysis protocols. No human data annotations are required, which allows large numbers of examples to be used, enabling the potential of the deep-learning technology to be fully exploited.

Self-Learning Microscopy

After a one-time training phase, scanR AI enables the system to automatically analyze new data by incorporating the learned analysis protocol into its assay-based workflow. Because the user has full control in designing the training experiment and many challenging analysis conditions can be covered during the training phase, the accuracy and robustness of the analysis results are improved.

Robust, Fast and Automated Image Acquisition and Analysis

The scanR system performs fully automated image acquisition and analysis of multiwell plates, slides and custom-built arrays. Throughout the automated image acquisition, the scanR system maintains the focus plane using a combination of software algorithms and hardware, including TruFocus Z-drift compensation. Images are automatically analyzed during acquisition to minimize analysis time, and all units are precisely synchronized by a real-time controller to maximize the acquisition speed.

Simple Workflow and Fast Setup to Ease Research

The scanR HCS station combines these benefits with a user-friendly workflow that requires less human interaction, even during the AI training stage. The responsive interface contributes to intuitive, straightforward analysis. This makes it easy for life science and pharmaceutical researchers to harness the power of HCS data while benefitting from a fast, simple setup.

Do you use Olympus products in your lab? Write a review today for your chance to win a $400 Amazon gift card>>

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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Digital MicroscopyDigital microscopy involves using digital cameras and sensors to capture high-resolution images of samples for analysis. It offers enhanced imaging capabilities compared to traditional optical microscopy and is widely used in biological and material science research. Explore digital microscopy systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Cell-Based PlatformMicroscopyMicroscopy is a technique used to observe small objects in detail, from cells to materials, using light or electron microscopes. It enables researchers to examine structures with high resolution, aiding in fields such as biology, medicine, and materials science. With advanced microscopy techniques, scientists can gain insights into cellular processes, tissue structures, and material properties. Explore the best microscopy solutions in our peer-reviewed product directory, compare products, read customer reviews, and get pricing directly from manufacturers.High Content ImagingHigh content imaging is a method combining two or more fluorescent microscopy experiments to identify substances that alter a cell’s phenotype in a desired manner. The process is adapted to multi-well plates and both the image acquisition and analysis are automated.Phenotypic ScreeningPhenotypic screening assesses cellular responses to compounds, enabling drug discovery and target identification. This technique is pivotal in finding effective treatments for complex diseases. Discover phenotypic screening platforms and tools with peer-reviewed comparisons and pricing in our directory.Digital ImagingDigital imaging is a technique that captures images of biological and chemical samples in high resolution, often using advanced cameras and sensors. This technology is crucial in microscopy, diagnostics, and quality control. Explore digital imaging systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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Rapidly acquire quantitative data from cell-based assays