Rapid Freezing of Tissue Samples

3 Apr 2011
bridget bridget
Laboratory Director

Product news

SP Scientific has launched the HistoChill™ - a new low temperature, mechanically refrigerated bath for the rapid freezing of tissue samples in Histology and Pathology Labs as well as other disciplines.

Operating down to -80°C, without the need for hazardous and costly expendable refrigerants, the compact tabletop HistoChill freezes tissues in just seconds increasing your lab throughput. Using a liquid medium, the HistoChill rapidly and thoroughly freezes samples minimizing ice crystal formation compared with the slow freezing rates encountered in a cryotome.

Frost build-up is minimized while introducing and extracting samples from the bath through integration of a warming loop on the upper outside wall of the refrigeration chamber. A hinged and insulated lid provides easy access to the bath.

The HistoChill is available in two configurations: the basic HistoChill for general freezing applications and the advanced model with built-in magnetic stirrer and temperature control for more demanding tissue specific or R&D applications. The advanced model includes digital set point and temperature indication.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Refrigerators Freezers and CryogenicsRefrigerators, Freezers & Cryogenics can be used for preservation or experimental purposes. Types of freezers include deep freeze, -80C°C, ultra-low temperature, explosion proof, cryogenic and controlled rate freezers. Freezing is also used in freeze-drying equipment for dehydration processes. Feature to consider in freezers include temperature control and recorders, failure alarms and self-closing mechanisms.Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.