QIAGEN Partners with Leading European Service Provider GATC Biotech to Offer Clients Full Access to Ingenuity Variant Analysis

19 Mar 2015

Industry news

QIAGEN N.V. today announced a commercial agreement with GATC Biotech to provide GATC clients full access to QIAGEN’s Ingenuity® Variant AnalysisTM solution for analysis and interpretation of genetic data. GATC is one of Europe’s leading providers of DNA and RNA sequencing services to customers worldwide. The access will take the form of interpretation services and direct access to Ingenuity Variant Analysis as a feature of the GATC Biotech’s services.

Ingenuity Variant Analysis is a powerful bioinformatics platform enabling laboratories to efficiently evaluate data generated by high-throughput next-generation sequencing (NGS) technologies. The QIAGEN software quickly filters genetic variants in a secure, private cloud-based environment to identify variants most likely to cause disease, drawing upon the industry-leading Ingenuity Knowledge Base.

Dr. Marcus Benz, Chief Operating Officer of GATC Biotech, commented: “This new commercial agreement with QIAGEN provides our customers with full access to the Ingenuity software enabling rapid analysis and interpretation of next-generation sequencing data in terms of relevant genetic variations. We are offering our clients a unique, fully integrated one-stop solution. GATC Biotech selected the Ingenuity Variant Analysis solution as a perfect match. Integrating this software tool with our InViewTM Human Exome product enables us to provide world-class data analysis for end-users of NGS, including clinical and laboratory geneticists and other professionals investigating diseases.”

“We are very pleased to partner with GATC Biotech, a respected provider serving more than 10,000 customers in academia and industry. Offering Ingenuity Variant Analysis to GATC Biotech clients, integrated with their own InViewTM Human Exome NGS solution, further expands the growing global presence of our solution for analysis and interpretation of NGS data,” said Dr. Laura Furmanski, Senior Vice President of QIAGEN and head of the Bioinformatics Business Area. “As next-generation sequencing spreads and its focus moves from data generation to interpretation, QIAGEN’s leadership in bioinformatics solutions enables laboratories and clinicians to move rapidly from raw data to valuable insights.”

QIAGEN offers industry-leading applications for the analysis, interpretation, and reporting of biological data through a diverse portfolio of solutions that include the Ingenuity, CLC bio and BIOBASE product lines. Ingenuity Variant Analysis is the world’s leading solution for analysis and interpretation of human sequencing data generated with NGS technologies. The web-based software leverages the Ingenuity Knowledge Base, a repository of expertly curated biological interactions and functional annotations created from millions of individually modeled relationships between proteins, genes, complexes, cells, tissues, drugs, and diseases. Data from more than 300,000 samples have so far been analyzed using Ingenuity Variant Analysis, which has helped to further expand the power of the Knowledge Base.

The agreement with GATC Biotech is non-exclusive, and financial terms were not disclosed.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.SNPs TechnologySingle nucleotide polymorphisms (SNPs) are individual base variations in a DNA sequence. SNPs are used in research to study predispositions to disease and drug discovery. Products for studying single nucleotide polymorphisms include SNP arrays and detection systems to detect polymorphisms, SNP typing systems for genotyping DNA, and PCR to amplify specific SNPs.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.NGS SoftwareGenetic Variation