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QIAGEN Launches ScreenGel Software for QIAxcel® Multicapillary Gel Electrophoresis Systems

QIAGEN
8 Feb 2011
Sarah Sarah
Marketing / Sales

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QIAGEN launches ScreenGel software for convenient DNA fragment and RNA analysis with the QIAxcel® multicapillary gel electrophoresis systems. The software combines the highest possible flexibility for researchers with the ability for standardized and reproducible operations in routine labs.

ScreenGel enables the easy performance, interpretation and customized documentation of electrophoresis analysis. It facilitates system setup and data analysis with an intuitive user interface for easy navigation. Performance of runs is supported by “wizards” that guide users step-by-step through the experiment setup.

The software supports electronic record requirements specified under 21 CFR part 11, and enables standardized sample processing with process templates that cover the entire workflow as well as secure user management with a variety of access levels. ScreenGel is backwards compatible with the previous BioCalculator software, thereby allowing the use of past experiment files and seamless installation on existing QIAxcel systems.

The software is launched together with the new QIAxcel Advanced system which comes with improved hardware features and a new look and feel. The system enables effortless automated electrophoresis, which replaces traditional labor-intensive gel analysis of DNA and RNA, streamlines the workflow and significantly reduces time to result. Ready-to-go gel cartridges allow processing of up to 96 samples without manual intervention, thus reducing manual handling errors and eliminating the need for tedious preparation, time consuming data acquisition and analysis. The system can separate fragments with only a few base pairs difference in size in less than 10 minutes while processing 12 samples in parallel.

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ElectrophoresisElectrophoresis equipment is used to separate mixtures of protein, DNA or RNA, based on their electric charge, size and other physical characteristics, by passing them through a medium such as a polyacrylamide gel, an agarose gel or a capillary tube. Electrophoresis equipment includes horizontal and vertical gel electrophoresis chambers, isoelectric focusing systems, 2D electrophoresis and capillary electrophoresis instruments. Precast gels with a gradient can be used or gels can be hand cast. Samples are run alongside ladders or markers to identify the approximate size of a molecule. Separated proteins and nucleic acids in the gel can be stained or probed with fluorescent markers and then imaged and detected using gel documentation instruments, transilluminators, densitometers and scanners. Find the best electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.RNA InterferenceRNA interference (RNAi) uses siRNA or miRNA for transcriptional silencing, gene knockdown and regulation of gene expression. RNAi requires chemical synthesis, introduction of DNA vectors into cells, an assay of RNAi effects and RNAi quantification or analysis. Consider target sequence selection, reagent preparation, controls, high specificity and effectiveness and low non-specific gene knockdown.

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QIAGEN Launches ScreenGel Software for QIAxcel® Multicapillary Gel Electrophoresis Systems