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Protein Forest Delivers Digital ProteomeChip System to Thermo Fisher Scientific

Protein Forest, Inc.
13 Nov 2008
Emily
Student / Graduate

Product news

Protein Forest®, a leading developer of state-of-the-art sample fractionation technology and bioinformatics software for protein research, today announced that it has commenced shipments of its new digital ProteomeChipTM (dPCTM) protein separation system.

The ProteomeChip system fractionates and concentrates proteins or peptides by isoelectric focusing. It provides higher resolution, greater reproducibility, faster analyses, and easier operation than traditional gel-based protein separation techniques.

Also shipping is Protein Forest’s Mass Spec Results and Analysis ToolTM (MSRATTM) bioinformatics software. The MSRAT software is designed to help mass spectrometrists, protein chemists, and other researchers interpret the results of experiments that incorporate dPC technology.

The first ProteomeChip system and MSRAT software were delivered to the proteomics group at Thermo Fisher Scientific, the leading developer and manufacturer of mass spectrometric systems for proteomics research. Researchers at Thermo Fisher will use the dPC system with their state-of-the-art ion trap, OrbitrapTM, and triple quadrupole mass spectrometer systems on a variety of challenging proteomics research projects.

“We are proud to work with Protein Forest.” said Andreas Hühmer, Ph.D., Director of Proteomics at Thermo Fisher Scientific. “We see the dPC as technology that could be a superior alternative to 2D gels, SDS-PAGE, and HPLC-based sample preparation methodologies in many workflows, and improve the quality and quantity of protein research results.”

“We are very pleased that Thermo Fisher Scientific will be using our dPC products. We expect Thermo Fisher scientists to validate the multiple benefits of dPC systems and MSRAT software for mass spectrometry-based proteomics research.” said Russell Garrick, Ph.D., President and CEO of Protein Forest.

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ElectrophoresisElectrophoresis equipment is used to separate mixtures of protein, DNA or RNA, based on their electric charge, size and other physical characteristics, by passing them through a medium such as a polyacrylamide gel, an agarose gel or a capillary tube. Electrophoresis equipment includes horizontal and vertical gel electrophoresis chambers, isoelectric focusing systems, 2D electrophoresis and capillary electrophoresis instruments. Precast gels with a gradient can be used or gels can be hand cast. Samples are run alongside ladders or markers to identify the approximate size of a molecule. Separated proteins and nucleic acids in the gel can be stained or probed with fluorescent markers and then imaged and detected using gel documentation instruments, transilluminators, densitometers and scanners. Find the best electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Ion ChromatographyIon chromatography, also known as ion exchange chromatography, is a high-performance liquid chromatographic technique used for the separation and identification of ions or polar molecules in a sample, including proteins, nucleotides and amino acids. Equipment includes ion exchange columns, ion exclusion columns, ion chromatography systems, pumps, and detectors. Find the best ion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Protein Forest Delivers Digital ProteomeChip System to Thermo Fisher Scientific