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Protea Release New LC Column Line for Protein Separations

Protea Biosciences Group, Inc
28 Jan 2013

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Protea Biosciences Group, Inc. a leading developer of new bioanalytical technologies, announced at the ASMS Sanibel Conference the introduction of Amplus® wide-pore core shell HPLC columns, a new line of liquid chromatography columns specifically designed for intact protein analysis.

This new family of HPLC silica-based columns employ core shell technology combined with a specific porosity designed to facilitate proteins separation, including those with high molecular weight.

“This year the ASMS Sanibel Conference is focused on Top Down proteomics applications and we thought it was a great opportunity to introduce a new technology designed for intact protein chromatographic analysis,” stated Alessandro Baldi, PhD, Vice President and General Manager of Protea Biosciences. ‘Amplus’ technology provides scientists with high chromatographic efficiency and facilitates Top Down proteomics approach to study intact proteins with or without mass spectrometry.”

Amplus, the new brand of analytical columns, has been developed in collaboration with the Japanese firm CromaNik Technologies and it is available in different chemistries and porosities to facilitate and resolve the most difficult separations in Top Down proteomics studies.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.

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Protea Release New LC Column Line for Protein Separations