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Protea Introduces the GPR-850 Gel Protein Recovery System

Protea Biosciences Group, Inc
31 Jan 2014
Lois Manton-O'Byrne, PhD
Executive Editor

Product news

The GPR® System delivers efficient recovery of gel separated intact proteins through a multiplexed, automated, microfluidics chip-based process.

The Gel Protein Recovery (GPR) System empowers you with an easy and efficient system for intact protein recovery from polyacrylamide gels. Using the GPR-850 instrument, GPRchips™, and GPR reagents, you will recover molecules for subsequent top-down proteomics to facilitate effective protein identification, characterization, and quantitation by mass spectrometry, all while boosting your efficiency.


Efficiency
Advanced microfluidic GPRchip allows for effective protein extraction from gels.
An automated process in a molecule friendly physico-chemical environment.

High Throughput
Eight-channel parallel processing can simultaneously extract proteins from 8 different gel spots.
8 channel extraction time < 20 min.

Non-disruptive Workflow
Microfluidic analytical path provides efficient recovery and a smooth workflow.
Preserves sample integrity for accurate information.

Ease of Use
Standardizes workflow and provides access to protein recovery to everyone in the lab.
Effective top-down proteomics is made accessible by automation and specialized chemistries.

Personality
Experience the GPR-850 with unique color options!

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Protea Biosciences Group, IncCompany website

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ElectrophoresisElectrophoresis equipment is used to separate mixtures of protein, DNA or RNA, based on their electric charge, size and other physical characteristics, by passing them through a medium such as a polyacrylamide gel, an agarose gel or a capillary tube. Electrophoresis equipment includes horizontal and vertical gel electrophoresis chambers, isoelectric focusing systems, 2D electrophoresis and capillary electrophoresis instruments. Precast gels with a gradient can be used or gels can be hand cast. Samples are run alongside ladders or markers to identify the approximate size of a molecule. Separated proteins and nucleic acids in the gel can be stained or probed with fluorescent markers and then imaged and detected using gel documentation instruments, transilluminators, densitometers and scanners. Find the best electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Medicinal ChemistryMedicinal chemistry is a broad discipline encompassing the design, identification, synthesis and development of chemicals in drug discovery. It includes a number of techniques covering structural biology, synthetic chemistry and molecular biology. Technologies used in medicinal chemistry include ADME, lab-on-a-chip, high content screening and assay assembly.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Solid-Phase ExtractionSolid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Protein ExpressionMicrofluidicsMicrofluidics is the science of manipulating small volumes of fluids in micro-sized channels. It is widely used in diagnostics, drug development, and lab-on-a-chip technologies. Microfluidic devices can enable rapid, cost-effective, and high-throughput analysis of biological samples. Browse our peer-reviewed product directory to find the best microfluidic devices, compare products, check reviews, and get pricing directly from manufacturers.

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Protea Introduces the GPR-850 Gel Protein Recovery System