Products and services for diversifying preclinical models

AMSBIO has expanded its range of products and services dedicated to assisting scientists diversify their preclinical models effectively

7 Mar 2024
Will Thompson
Editorial Assistant

Industry news

amsbio-logo-2024

AMSBIO discusses the use of a proposed intestinal organoid biobank to combat accessibility issues as well as raising the issues of the lack of reporting by gender in COVID-19 vaccine development, where women had a disproportionate number of adverse-effects, under-reported due to aggregated data.

Until 1993, most clinical trial participants were men of European descent, leading to a lack of data on the safety and efficacy of treatments for women and diverse populations. Although attitudes in clinical trials are changing, inclusivity in preclinical research is still often overlooked, leading to critical gaps in the understanding of how drugs and treatments affect different populations even before they proceed to human trials.

AMSBIO is a global provider of human and animal biospecimens to help increase diversity in research. The company’s extensive biorepository houses an array of tissues from reliable sources, including a comprehensive selection of healthy tissues as well as a variety of disease states from different genders and ethnicities.

For specific research needs, AMSBIO additionally offers a custom tissue procurement service to supply the samples to match your research demands, however complex the donor demographics required. In addition, leveraging a combination of novel organoids with proprietary lab-on-a-chip technology – AMSBIO is uniquely placed to help preclinical researchers cost effectively develop high throughput data-rich assays.

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Lab-on-a-ChipLab-on-a-chip (LOC) technology uses microfluidic chips, such as microarrays, to perform biochemical assays on a small scale. Benefits of lab-on-a-chip include the small volume of sample required as well as the speed of analysis. In selecting lab-on-a-chip devices consider the assay, cost, reliability, sensitivity and signal to noise ratio.Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.Animal ModelsThe use of non-human animals in experiments or behavorial observations. The research is conducted inside universities, medical schools, pharmaceutical companies, farms, defence establishments, and commercial facilities that provide animal-testing services to industry. It includes pure research such as genetics, developmental biology, behavioral studies, as well as applied research such as pharmaceutical testing in pre-clinical, before human, studies. RegulatoryPharmaceutical regulations impact on all areas of drug development, manufacture and control and supply. Services are provided from the early stages of drug development and clinical trials through to dossier submission, approval and marketing. Regulatory also includes submission of analytical studies from the pharmaceutical product and safety. Tissue ProcessingTissue processing involves preparing biological tissue samples for microscopic analysis, including fixation, embedding, and sectioning. This process is essential for histopathology and diagnostic applications. Explore tissue processing products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Organoids
Products and services for diversifying preclinical models