PreOmics launches BeatBox at ASMS 2021 for high-throughput tissue homogenization

New sample preparation tool promises to provide higher extraction of proteins from cells and tissues with minimal cross-contamination

10 Nov 2021
Blake Forman
Content Creator

Product news

PreOmics, a developer of innovative tools for mass spectrometry-based protein analyses, has announced the launch of BeatBox, its new sample preparation tool for tissues and cells. BeatBox delivers tissue homogenization in a simple, fast and easy-to-use format and can process up to 96 tissue samples in 10 minutes from 1-5 mg of tissue, with no cross-contamination.

The BeatBox fits on a benchtop, is quiet, and can be seamlessly integrated with PreOmics iST sample preparation workflows for mass spectrometry-based protein analysis. The PreOmics Tissue Homogenization add-on kit uses proprietary coated GYUTO bead technology where only the GYUTO bead is in motion for the duration of the assay, which generates well homogenized samples from a wide variety of tissues & cells.

In a recent comparison with two commercial homogenizers at a world-leading proteomics research laboratory, the BeatBox was shown to provide higher extraction of proteins from limited tissue inputs (1-2mg), the highest throughput, an improvement in reproducibility of 2.5x across different tissue types and the fastest processing time of just 10 minutes.

Nils A. Kulak and Garwin Pichler, Managing Directors, PreOmics, commented: “A reproducible and reliable proteomics tissue homogenization process needs to release the maximum amount of protein, maintain sample integrity and minimize cross-contamination. Users currently have to contend with the space occupied by the large homogenization instruments, the noise made by some processes and the challenges that come with managing costs while wanting to process high sample numbers.

“With BeatBox, researchers can achieve fast, accurate tissue homogenization, simply and affordably enabling processing of large tissue biobanks. We believe this is a leap forward in tissue preparation efficiency and are excited to be unveiling BeatBox to the mass spectrometry community at ASMS 2021. We also look forward to bringing a succession of new technologies based on this platform to the market in the coming years.”

PreOmics improved sample technology enables robust and reproducible sample preparation. The iST technology provides significant time savings as complex workflows
requiring many different reagents that previously took 48 hours are replaced by a single kit containing all standardized reagents.

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Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Protein QuantificationThe detection and quantification of proteins in a sample is vital across life sciences, pharmaceutical research and clinical diagnostics, and a variety of equipment is available to scientists to simplify the workflow. Proteins of interest can be easily labeled and detected on light-based detection instruments. Immunoassay kits allow you to identify a specific protein of interest and protein detection beads or antibody microarrays allow you to identify multiple specific proteins at once. Protein interactions and enzyme activity can also be monitored with protein-protein interaction assays. Additionally, the biophysical characterization of proteins is made easy with biokinetic analyzers. Find the best protein detection and quantification products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Sample HomogenizerProteomicsProteomics refers to the analysis of proteins through a variety of different experiments in order to understand structure and functionality. Typical techniques include protein purification and mass spectrometry.
PreOmics launches BeatBox at ASMS 2021 for high-throughput tissue homogenization