Powder Testing Instrumentation, Comprehensive Methodologies and Extensive Experience Add Up to Unique Offering

2 Feb 2009
Emily Marquez-Vega
Publishing / Media

Product news

The theme for Freeman Technology at Interphex 2009 (17-19 March, New York) will be the company’s complete offering for pharmaceutical processors. Freeman’s FT4 powder tester, backed by a unique process-focused approach to powder characterization, delivers the critical insight into powder behaviour that companies need in order to understand their powders, achieve compatibility between powder and plant, and enable process optimization - supporting the aims of QbD.

The FT4 performs a range of methodologies, measuring shear, bulk and dynamic properties in a short time, using relatively small amounts of material. Freeman’s approach to interpreting the data generated makes extensive use of the company’s know-how, as well as the processor’s own experience. The results often indicate why some formulations are ‘easy’ to manufacture and others are not. This knowledge is the foundation of efficient processing and informs the development of formulations that will process well, with the required performance characteristics.

In addition, it is possible to define, in terms of easily measurable parameters, the characteristics of materials that will be optimal for a given piece of plant - a hopper or a tablet press, for example. Developing formulations that meet this specification ensures compatibility between the plant and powder, building quality into the manufacturing process from the outset, as advocated by QbD.

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Particle CharacterizationParticle characterization instruments are used to determine particle size distribution, shape, surface area, zeta potential, density and porosity of particles and materials. Multiple tecchniques are available for determining particle size, shape and count including dynamic light scattering (DLS), laser diffraction, electrozone (Coulter technique), imaging particle analysis and single particle optical sensing. Determine the density of your material with a gas pycnometer or examine its surface area and porosity with gas adsorption analyzers and mercury porosimeters. Find the best particle characterization instruments in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.