Positive Procedural Control with CD Markers for Immunophenotyping

9 Nov 2012

Product news

Streck, Inc. has introduced CD-Chex™ Select, the first and only commercially-available flow cytometry control with a selected group of CD markers used for immunophenotyping. The product is an assayed positive procedural control for reagent staining, erythrocyte lysis, sample preparation and instrument performance. CD-Chex Select complements the full line of Streck CD-Chex flow cytometry controls.

Sample 1 provides % positive values for CD markers including CD26, CD41, CD57, CD64, FMC7, TCR α/β, TCR γ/δ. Sample 2 provides % positive values for epitopes CD58 and CD61, in addition to intracellular markers CD79a and MPO.

CD-Chex Select can be handled like a patient sample. The product eliminates the need for laboratories to hold and validate patient samples to use as a control for the selected markers. The established means and ranges provide pathologists with confidence in their instrument results.

CD-Chex Select features 30-day open-vial stability and 90-day closed-vial stability. Plastic 3.0ml cap-pierceable vials are compatible with automated sample preparation instruments, including BD Biosciences and Beckman Coulter® systems.

The CD-Chex Select is currently for Research Use Only and not for use in diagnostic procedures.

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Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.Immunophenotyping