SelectScience
Join Free
Accelerating Science
NewsLife Sciences

Porvair Sciences launches new columns for rapid removal of gDNA from RNA samples

Porvair Sciences Ltd
26 May 2021
Tom Casburn
Associate Editor

Product news

Porvair Sciences has launched Chromatrap® gDNA Removal Columns that quickly remove unwanted genomic DNA (gDNA) from RNA samples.

Removal of gDNA from RNA samples is of particular importance to scientists undertaking RT-PCR, RNA-seq, and microarray-based applications where the high purity and accurate measurement of RNA is vital.

Employing a simple load and spin method the new columns efficiently capture gDNA on the membrane allowing efficient flow-through of DNA-free cell lysates for downstream RNA purification. Unlike traditional gDNA removal methods - Chromatrap® gDNA removal columns require no time-consuming enzymatic digestion that can also impact RNA purity.

Beneficially using the Chromatrap® spin column methodology the captured gDNA may also be eluted for use in downstream applications such as g PCR, Southern blotting, cloning, and sequencing.

For more of the latest science news, straight to your inbox, become a member of SelectScience for free today>>

Links

Porvair Sciences LtdCompany website

Tags

DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA / RNA QuantificationDetection and quantification of nucleic acids is important in molecular biology, cloning, expression, forensics and clinical diagnostics. Nucleic acids can be detected by labeling with colorimetric, fluorescent or radio labels and using in situ hybridization kits to identify specific sequences. Multiple nucleic acids can be detected and quantified at once using RNA / DNA detection beads or RNA / DNA microarrays. Find the best DNA / RNA Quantification products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.PurificationPurification techniques are essential for isolating compounds of interest from complex mixtures, such as proteins, nucleic acids, and chemicals. These techniques are critical in biochemistry, drug development, and environmental studies. Explore purification systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.DNA ExtractionDNA extraction is a critical step in many biological studies, including genomics, diagnostics, and forensic analysis. The process involves isolating DNA from cells or tissues, and the quality and purity of the extracted DNA can impact downstream applications. Explore DNA extraction products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.DNADeoxyribonucleic Acid (DNA) is the main component of chromosomes and the carrier of genetic information of living organisms. Find out here about PCR, NGS, ChIP-Seq, gel imaging, and many other techniques which can be used for the analysis of DNA.RNARNA is a nucleic acid that plays a key role in gene expression and protein synthesis. It serves as a messenger between DNA and ribosomes, carrying genetic instructions to produce proteins. Advances in RNA-based therapies, such as mRNA vaccines and gene editing, have revolutionized treatment strategies for genetic disorders and infectious diseases. Explore RNA research tools and therapies in our peer-reviewed product directory; compare products, check customer reviews, and get pricing directly from manufacturers.

Related articles