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Polyplus acquires e-Zyvec to expand expertise in plasmid DNA vector engineering

Polyplus Transfection

The partnership hopes to bolster the effort to provide commerical-grade cell and gene therapy solutions

1 Feb 2022
Rory Shadbolt
Publishing / Media

Industry news

Polyplus, a leading provider of upstream process solutions for advanced biologic and cell and gene therapy production from research to commercial-grade has announced the acquisition of e-Zyvec, a provider of DNA design and production services for tailor-made DNA vectors for gene therapy, bio-manufacturing, and research. Financial details were not disclosed.

“When we launched e-Zyvec 5 years ago, the idea was to bring a different type of genetic engineering service to the market, leveraging today’s digital technology. Moving forward, we are excited to now join an established market leader like Polyplus where we will have the resources and capacity to continue developing and growing the e-Zyvec platform,” said Sylvain Julien, President, and Co-Founder at e-Zyvec.

“Thanks to our innovative conception and assembly of DNA molecules, we are able to propose tailor-designed vectors that provide options that add value to each customer process. Joining the Polyplus team is an organic transition for our team, enabling us to expand this technology across the global market. Our full team will carry forward in their current roles, delivering a layer of expertise and human capital that is invaluable in today’s market,” said Carine Morel, Managing Director, and Co-Founder at e-Zyvec.

“Polyplus is evolving and growing, and this latest acquisition is an example of our strategy in action. We will continue to build out the existing portfolio, which is strong on its own, by adding complementary activities that make us a more effective and comprehensive partner to our customers, with a focus on expanding process economics optimization efforts for cell and gene therapy developers and manufacturers,” Mario Philips, CEO of Polyplus commented.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.DNADeoxyribonucleic Acid (DNA) is the main component of chromosomes and the carrier of genetic information of living organisms. Find out here about PCR, NGS, ChIP-Seq, gel imaging, and many other techniques which can be used for the analysis of DNA.TransfectionTransfection introduces nucleic acids (DNA or RNA) into cells, facilitating gene expression, genome editing, and functional studies. It�s widely used in genetic research, drug discovery, and therapeutic development. Find transfection reagents, kits, and systems in our product directory with reviews and pricing options.Cell TherapyCell therapy involves using living cells to treat diseases, often by replacing damaged cells or stimulating regeneration. Stem cell therapy and CAR-T cell therapy are examples of cutting-edge treatments in regenerative medicine and cancer immunotherapy. Browse our peer-reviewed product directory to find the best cell therapy tools, compare products, check reviews, and get pricing directly from manufacturers.Gene TherapyGene therapy is a technique that modifies or replaces genes within an individual's cells to treat or prevent diseases. This approach holds potential for curing genetic disorders, cancers, and certain viral infections. Advances in gene editing technologies like CRISPR are driving the growth of gene therapy. Explore gene therapy tools and technologies in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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Polyplus acquires e-Zyvec to expand expertise in plasmid DNA vector engineering