Phenomenex Introduces SFC Columns for Analytical and Preparative Applications

16 Dec 2008
Samantha Rosoman
Campaign Coordinator

Product news

Phenomenex Inc., a global leader in the manufacture of separation science consumables, announces a new line of supercritical fluid chromatography (SFC)-certified columns. These new columns bring new phases and selectivities to SFC separations, expanding the application of this technology to analytical and preparative applications. Interest in SFC is growing because it offers several advantages over HPLC including improved resolution, faster separations and higher throughput. The technique also reduces the use of toxic solvents, meeting demands for “greener” solutions. SFC columns have application in pharmaceutical and academic research as well as medicinal chemistry.

Phenomenex’s new SFC offerings represent three of the company’s media brands including the Luna® HILIC (hydrophilic interaction liquid chromatography) columns with unique, cross-linked diol chemistry for analysis of polar metabolites; Synergi™ Polar-RP (ether-linked phenyl phase) for polar and aromatic analysis; and the new Lux™ chiral phases.

“Selectivity choices are important in method development,” explained Terrell Mathews, strategic product manager for Phenomenex. “The same differences in selectivity offered by achiral HPLC columns can now be evaluated for SFC separations.”

Phenomenex is a global technology leader committed to developing novel separation, purification and analytical chemistry solutions for the life sciences and related industries. Phenomenex’s core technologies include products for liquid chromatography, gas chromatography, sample preparation, bulk purification chromatographic media, and chromatography accessories and equipment. For more information on Phenomenex please click on the company webpage link on the right.

Synergi Full Range Selectivity LC Columns

Phenomenex Inc

Full Range SelectivityFour unique phases developed to provide a different selectivity for successful separations of the most complex mixtures and challenging analytes under reversed phase conditions. Whether your compounds are hydrphobic or polar, Synergi columns provide you with a full range of selectivity, ensuring separation of the most challenging and complex mixtures.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Preparative ChromatographyPreparative chromatography equipment is used for purification purposes, separating and collecting compounds eluted from a mixture which can then be subsequently used for further purposes. This can be done in large quantities or small. Preparative chromatography systems are usually low to medium pressure liquid chromatographs that are semi-automated. Explore a range of preparative columns and fraction collectors. Find the best preparative chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.