Phenomenex Introduce New 5-Micron C8 Kinetex Core-Shell for Difficult-to-Resolve Compounds

4 Jun 2013

Product news

Phenomenex Inc., a global leader in the research and manufacture of advanced technologies for the separation sciences, introduces the Kinetex C8 5-micron core-shell HPLC column. The widely used C8 phase delivers optimum retention for the analysis of hydrophobic and “sticky” compounds. In combination with Kinetex Core-Shell Technology, this phase gives analysts an excellent high-performance reversed phase alternative for HPLC methods. As with the existing Kinetex 5-micron C18 and XB-C18 phases, the new 5-micron C8 core-shell column can be easily substituted into methods that meet United States Pharmacopeia and European Pharmacopoeia requirements. Specifically the Kinetex 5-micron C8 meets USP specifications for Classification Code L7, enabling laboratories using 5-micron L7 columns to realize the performance benefits of Kinetex Core-Shell Technology without adjusting their USP methodology.


The largest diameter particle in the family, Kinetex 5-micron core-shell media delivers better performance than 3 and 5-micron fully porous offerings, with no increase in backpressure. In fact, the new 5-micron media provides 90 percent higher average efficiencies compared to the same size fully porous columns with little to no method development. Kinetex 5-micron C8 columns are fully scalable to or from the 1.7- and 2.6-micron particles, enabling easy method transferability.


“This new 5-micron phase expands our ever-growing Kinetex product line, which meets customers’ needs from UHPLC to HPLC to small-scale preparative purification,” comments Simon Lomas, brand manager for Phenomenex. “Kinetex Core-Shell Technology delivers huge performance advantages over conventional, fully porous media, such as sharper peaks, reduced run times, and more smiles in the lab.”

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.HPLC Method DevelopmentIt is important to develop and validate HPLC methods in order to identify, quantify or purify compounds of interest in the most efficient way. Effective method development ensures optimization, quality control and cost effectiveness.ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.PurificationPurification techniques are essential for isolating compounds of interest from complex mixtures, such as proteins, nucleic acids, and chemicals. These techniques are critical in biochemistry, drug development, and environmental studies. Explore purification systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.
Phenomenex Introduce New 5-Micron C8 Kinetex Core-Shell for Difficult-to-Resolve Compounds