Personalized Cancer Diagnostics to be Developed on the BD MAX™ Platform

14 Oct 2012

Product news

BD Diagnostics, a segment of global medical technology company BD (Becton, Dickinson and Company), and Lab21, a global leader in personalized healthcare diagnostics, have announced today that they will collaborate to develop oncology assays for the BD MAX™ fully automated, bench-top molecular system.

As part of the collaboration, Lab21 will develop polymerase chain reaction-based assays to be performed on the BD MAX platform from BD Diagnostics. These assays will identifty a series of oncology markers. BD will manufacture and commercialize these tests worldwide.

The first two assays will be designed to detect mutations in the KRAS and BRAF genes, which are found in several types of cancer. These initial assays were selected because of their current importance in optimizing the management of cancer patients. The agreement also includes the development of novel nucleic acid extraction procedures from formalin-fixed paraffin-embedded tissue.

This collaboration will enable BD Diagnostics to offer personalized cancer diagnostics on the BD MAX system for the first time.

“When used in conjunction with other laboratory and clinical information, these assays will provide critical input to support oncologists and their patients in making more informed decisions about their care,” said Tom Polen, President, BD Diagnostics – Diagnostic Systems.

Graham Mullis, CEO of Lab21, added, “We are pleased to expand our partnership with BD from the detection of Aspergillus species to the broader development and commercialization of important diagnostic markers in the oncology area. Lab21 has significant experience with and proven assay development capability in cancer molecular diagnostics.”

Links

Tags

Gas ChromatographyGas chromatography (GC) is an analytical technique used to separate and quantitate mixtures of small and volatile compounds. Gas chromatographs or GC systems include components such as GC columns, detectors, pumps and autosamplers. Choose from packed or capillary GC columns, flame ionization (FID), photoionization (PID) electron capture detectors and selective or non-selective detectors. Find the best gas chromatographs in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiosensorsBiosensors are devices used to detect an analyte using biological molecules specific to the analyte coupled to a detector. Biosensor instruments may be photometric, typically using surface plasma resonance (SPR), electrochemical or QCM (quartz crystal microbalance) biosensors. Biosensors should be selective, portable, robust and sensitive and have a fast response time. Systems may be manual or automated and usually have associated software.PCR and Thermal CyclingPolymerase chain reaction (PCR) kits and thermal cyclers are used for the in vitro amplification of DNA permitting subsequent analysis and experimental procedures. Explore a range of high-quality polymerase, primers and nucleotides or simplify your workflow with a PCR mastermix. Find reverse transcription PCR (RT-PCR) and cDNA synthesis kits for RNA products and libraries. Quantitatively measure the amplification of DNA with real-time PCR (qPCR) and droplet digital PCR (ddPCR) kits and systems, and discover automated PCR setup solutions to increase throughput. Alternative DNA amplification methods also include recombinase polymerase amplification (RPA) kits. Find the best PCR kits and thermal cyclers and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Cancer DiagnosticsThere are a wide variety of diagnostic tests for cancer available, and this range continues to expand as our knowledge of cancer improves. Current diagnostic methods include biopsy, imaging and blood tests for known biomarkers. New methods in research development include liquid biopsies and cancer breathalyzers.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.BRAFKRASOlympics
Personalized Cancer Diagnostics to be Developed on the BD MAX™ Platform