PerkinElmer Launches New EnSpire Multilabel Plate Readers with Luminescence Capability, for Primary and Stem Cell Research

26 Oct 2009
Sarah Sarah
Marketing / Sales

Product news

PerkinElmer, Inc. has launched the latest expansion of the EnSpire™ Multilabel Plate Reader platform - EnSpire, with ultra sensitive luminescence detection. This new detection capability provides scientists, including those working with primary or stem cells in cancer and neuropharmacology research, with enhanced capabilities to improve assay performance and sensitivity.

The EnSpire platform features a configurable plate reader that delivers high performance detection and easy to use software. The affordable platform is adaptable for use in laboratories of many sizes with diverse research applications. This module expansion adds ultra sensitive luminescence detection, temperature control and fluorescence intensity (FI) bottom reading capabilities for both 96- and 384-well formats. Scientists working with limited numbers of cells can now generate enhanced assay signals, leading to improved assay performance and precision.

Nance Hall, vice president and general manager, Automation and Detection Solutions, Bio-discovery, PerkinElmer, said, "In areas where every cell is precious, and research resources are limited, EnSpire's luminescence sensitivity overcomes the challenges presented by applications where cell availability and low transfection rates may limit dynamic range and assay window optimization. The EnSpire platform, now with luminescence detection, enhances outcomesfor those researchers running luminescence studies, particularly cell proliferation, cytotoxicity, and reporter gene assays."

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High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.
PerkinElmer Launches New EnSpire Multilabel Plate Readers with Luminescence Capability, for Primary and Stem Cell Research