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PerkinElmer Launches LabChip® GX and GXII TouchTM Automated Gel Electrophoresis Systems

PerkinElmer
8 Jul 2014
Kerry Parker
CEO

Product news

New Automated Platform Provides Life Sciences Researchers with Precise Nucleic Acid Quantification and Protein Characterization

PerkinElmer, Inc., a global leader focused on the health and safety of people and the environment, today announced the launch of the new LabChip® GX Touch and GXII TouchTM automated electrophoresis systems. The LabChip platform’s key feature is automation of conventional gel electrophoresis, eliminating the need for manual sample preparation. The LabChip GX Touch and GXII Touch benefit customers by reducing hands-on time and simplifying data generation via a user friendly operator touch screen.

The LabChip platform provides the data and throughput necessary to perform effective nucleic acid quantification and protein characterization. The LabChip GX system can enhance genomics research process by precisely quantifying nucleic acids. The GXII Touch system helps to accelerate the development of biotherapeutic drugs by automating the protein characterization process.

“We launched the LabChip platform to provide enhanced workflows for genomics research as well as to speed up the discovery of breakthrough biotherapeutic drugs,” said Brian Kim, President, Life Sciences & Technology, PerkinElmer. “With these two new systems, scientists can harness microfluidics capabilities to obtain results more quickly and efficiently, improve their processes, and make significant research advancements.”

Current Quality by Design (QbD) initiatives underscore the need to identify and understand critical quality attributes, which are features of a therapeutic protein that affect its efficacy. Tight monitoring and control of these attributes helps to ensure stable, more predictable pharmacological response. The LabChip GXII Touch system’s rapid reporting of multiple protein critical quality attributes can support customer needs throughout the product life cycle.

The LabChip Touch platform’s top differentiator is its ability to perform electrophoresis in microfluidic channels. The LabChip GX Touch system provides rapid, quantifiable data for pre and post-PCR sample analysis, which is critical for next-generation sequencing and genomics workflows. The LabChip GXII Touch system quantifies protein attributes from process development through quality control in biotherapeutics development and manufacturing.

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Capillary ElectrophoresisCapillary electrophoresis (CE) is used to separate molecules based on charge, size and hydrophobicity. Pressure, voltage or a vacuum is used to introduce the sample to fused silica capillaries. Fluorescence, UV/Vis, UV or diode array detectors are used to visualize components. Types of CE systems include capillary electrochromatography (CEC), capillary zone electrophoresis and capillary gel electrophoresis. Find the best capillary electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein QuantificationThe detection and quantification of proteins in a sample is vital across life sciences, pharmaceutical research and clinical diagnostics, and a variety of equipment is available to scientists to simplify the workflow. Proteins of interest can be easily labeled and detected on light-based detection instruments. Immunoassay kits allow you to identify a specific protein of interest and protein detection beads or antibody microarrays allow you to identify multiple specific proteins at once. Protein interactions and enzyme activity can also be monitored with protein-protein interaction assays. Additionally, the biophysical characterization of proteins is made easy with biokinetic analyzers. Find the best protein detection and quantification products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.

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PerkinElmer Launches LabChip® GX and GXII TouchTM Automated Gel Electrophoresis Systems