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PerkinElmer Announces New Microplate Technology for High Throughput Screening

PerkinElmer
28 Jan 2008

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PerkinElmer Life and Analytical Sciences, a global leader in life science research, drug discovery and cellular science, today announced the launch of 20 new high-throughput microplates, which have been designed to augment the company’s instrumentation and assay platforms. An exclusive feature is an innovative plate height designed for 1536-well microplates. The unique design has the same dimensions as 96- and 384-well plates, provides a single automation protocol, and can significantly reduce error. Widely used in life science research and drug discovery labs, the microplate technologies were exhibited at LabAutomation 2008, Jan. 27-30, Palm Springs, Calif., booth #427.

“The microplate advancements demonstrate our commitment to optimize high-throughput screening and to support researchers, who must continually improve consistency in results, operational efficiency and error reduction,” said Dr. Richard Eglen, President, Molecular Medicine, PerkinElmer Life and Analytical Sciences.

With the new 1536-well microplate models, OptiPlate ™, CulturPlate ™, SpectraPlate ™ and AlphaPlate ™, there is no recalculation and height adjustment required when 96- and 384-well plates are changed to 1536-well plates. Many other 1536-well plates have heights of 8 or 10 mm, and involve two automation protocols. The new plates also have a wider gripping area, which enables more optimal robotic operations, and they meet standards established by the Society of Biomolecular Sciences (SBS) and the American National Standards Institute (ANSI).

The new light-gray AlphaPlate, which was designed specifically for AlphaScreen® and AlphaLISA™ biomarker detection assays, has been shown to significantly reduce crosstalk when compared to standard white 1536-well microplates. This provides for enhanced precision and greater sensitivity and signal amplification.

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MicroplatesMicroplates are multi-well plates used to increase the throughput of biological investigations. The number of wells microplates contain can range from 6 to 3243 wells, with the 96-well format being the most commonly used. Microplates can come tailored for a range of applications including cell culture, PCR, filtration, storage, non-binding surface, protein crystallization, as well as pre-coated, deep well and normal Standard microplates. Additionally, options for microplate colors include clear , black, white or black with clear bottom and white with clear bottom for absorbance microplate reader applications. Find the best microplates for your lab in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :

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PerkinElmer Announces New Microplate Technology for High Throughput Screening